Botulism history and symptoms

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]Associate Editor(s)-in-Chief: Michael Maddaleni, B.S.

Overview

Botulism symptoms ranges from mild to very severe in some cases. The common symptoms generally are nausea, vomiting, diarrhea and dysphagia. The common symptoms in adult are double vision, blurred vision and slurred speech. The common in the infants constipation and weak crying. Botulism affects mainly the nervous system and may lead to paralysis.

History and Symptoms

Botulism patients present with rapidly progressive neuromuscular malfunction. They can give history of eating rotten food specially fish in adults and honey in the children. Patients typically give history of diarrhea, nausea, vomiting and difficulty in swallowing.

	Adult botulism	Infant botulism
Most common symptoms	Adult botulism includes both the foodborne and the wound botulism. The most common symptoms of botulism include the following: Double vision Blurred vision Drooping eyelids (Ptosis) Slurred speech Difficulty swallowing Dry mouth Muscle weakness History of intravenous drug abuse (wound botulism) Vomiting Blatter	Infants less than 12 months of age are susceptible, with 95% of cases occurring between the ages of 3 weeks and 6 months of age at presentation. The mode of action of this form is through colonization by germinating spores in the gut of an infant. Symptoms include: Constipation Generalized weakness Loss of head control Like the other forms of botulism, the symptoms are caused by the absorption of botulinum toxin, and typically progress to a symmetric descending flaccid paralysis. Death is the eventual outcome unless the infant receives artificial ventilation.
Less common symptoms	Diarrhea	Weak cry Feeding difficulties

References

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