Roseola natural history, complications and prognosis

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief:

Natural history, complications and prognosis

Natural history

• The symptoms of roseola usually starts in the first 2 years of life of an infant. It starts as a high fever 40ºC (104ºF) which lasts for 3 to 5 days, as the fever abates, the child develops a non pruritic blanching papular or maculopapular rash that starts on the neck and progresses downward.
• The rash usually lasts for one or two days but may sometimes disappear within a couple of hours.

Complications

Roseola is usually benign and self limited. Complications may include:

• Seizures ( generally related to fever)
• Aseptic meningitis
• Encephalitis
• Thrombocytopenic purpura

Prognosis

• The prognosis of roseola is good. Without treatment, most children will recover without sequelae.