Esophageal candidiasis epidemiology and demographics

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1];Associate Editor(s)-in-Chief: Ahmed Younes M.B.B.CH [2]

Overview

Epidemiology and demographics

  • Esophageal candidiasis has not been adequately studied in immunocompetent individuals.
  • Candidiasis is the most common cause of infectious esophagitis followed by HSV esophagitis.[1]
  • In a study conducted in 2015, the prevalence of esophageal candidiasis was 11.2% in HIV infected individuals and 2.9% in HIV infected individuals.[2]
  • While esophageal candidiasis has been reported in 10-15% of immunocompromised patients during their lifetime.[3]
  • Autopsies revealed isolation of candida in 43% of immunocompromised individuals.[4]

References

  1. Chen LI, Chang JM, Kuo MC, Hwang SJ, Chen HC (2007). "Combined herpes viral and candidal esophagitis in a CAPD patient: case report and review of literature". Am. J. Med. Sci. 333 (3): 191–3. doi:10.1097/MAJ.0b013e318031b1f2. PMID 17496741.
  2. Takahashi Y, Nagata N, Shimbo T, Nishijima T, Watanabe K, Aoki T, Sekine K, Okubo H, Watanabe K, Sakurai T, Yokoi C, Mimori A, Oka S, Uemura N, Akiyama J (2015). "Upper Gastrointestinal Symptoms Predictive of Candida Esophagitis and Erosive Esophagitis in HIV and Non-HIV Patients: An Endoscopy-Based Cross-Sectional Study of 6011 Patients". Medicine (Baltimore). 94 (47): e2138. doi:10.1097/MD.0000000000002138. PMC 5059007. PMID 26632738.
  3. Underwood JA, Williams JW, Keate RF (2003). "Clinical findings and risk factors for Candida esophagitis in outpatients". Dis. Esophagus. 16 (2): 66–9. PMID 12823199.
  4. Weerasuriya N, Snape J (2006). "A study of candida esophagitis in elderly patients attending a district general hospital in the UK". Dis. Esophagus. 19 (3): 189–92. doi:10.1111/j.1442-2050.2006.00563.x. PMID 16722997.