Roseola epidemiology and demographics

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief:

Overview

Roseola is an illness of young children, with a peak prevalence between 7 and 13 months. Ninety percent of cases occur in children younger than two years. Roseola occurs equally in boys and girls. It occurs throughout the year, although outbreaks may occur in groups according to season .

Epidemiology and demographics

Prevalence

  • HHV-6 infection is detected in more than 90% of adult populations in developed countries.

Age

Roseola commonly affects young children between the ages of 7 and 13 months.[1]

Gender

  • Boys and girls are affected equally by roseola.[2]

Race

  • There is no racial predilection for roseola.

Developed countries

  • HHV6 infection is nearly universal accounting for 10-45% of febrile illness in infants.

Developing countries

  • There is a strong association of HHV6A in Zambian children when compared to rest of the world.

References

  1. JURETIC M (1963). "Exanthema subitum a review of 243 cases". Helv Paediatr Acta. 18: 80–95. PMID 13958107.
  2. Asano Y, Yoshikawa T, Suga S, Kobayashi I, Nakashima T, Yazaki T; et al. (1994). "Clinical features of infants with primary human herpesvirus 6 infection (exanthem subitum, roseola infantum)". Pediatrics. 93 (1): 104–8. PMID 8265302.