Cryptococcosis history and symptoms
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Serge Korjian M.D.; Yazan Daaboul, M.D.
Overview
The symptoms of cryptococcosis depend on the site of infection/clinical syndrome, the virulence of the yeast strain and the immune status of the host. Patients may be completely asymptomatic, or may have latent infection or symptomatic disease. As cryptococcus enters the body through the respiratory route, infection can present as pneumonia-like illness with fever, cough, sputum production and chest pain. Cryptococcus can also disseminate to the central nervous system and cause meningoencephalitis presenting with headache, nausea, vomiting, altered sensorium and focal neurological deficits.[1]
History and Symptoms
The symptoms of cryptococcosis depend on the site of infection/clinical syndrome, the virulence of the yeast strain and the immune status of the host. Patients may be completely asymptomatic, or may have latent infection or symptomatic disease. Because cryptococcus enters the body through the respiratory route, infection can present as pneumonia-like illness. Cryptococcus can also disseminate to the central nervous system and cause meningoencephalitis.
Cryptococcal Pneumonia
- Cough
- Shortness of breath
- Chest pain
- Fever
Cryptococcal meningitis
- Headache[2]
- Fever
- Neck pain
- Nausea and vomiting
- Sensitivity to light
- Confusion
References
- ↑ Secombe CJ, Lester GD, Krockenberger MB (2017). "Equine Pulmonary Cryptococcosis: A Comparative Literature Review and Evaluation of Fluconazole Monotherapy". Mycopathologia. 182 (3–4): 413–423. doi:10.1007/s11046-016-0065-9. PMID 27655152.
- ↑ Leonhard SE, Fritz D, van de Beek D, Brouwer MC (2016). "Cryptococcal meningitis complicating sarcoidosis". Medicine (Baltimore). 95 (35): e4587. doi:10.1097/MD.0000000000004587. PMC 5008555. PMID 27583871.