Diverticulitis pathophysiology

Diverticulitis Microchapters
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Cafer Zorkun, M.D., Ph.D. [2]

Pathophysiology

Pathogenesis

• Pathogenesis of diverticulitis includes three main processes which are change of the intestinal motility, increase of the lumenal pressure, and colonic microenviroment disorder which leads to infection after that.
• In a vivo test of diverticulitis patient colonic tissue with chemicals added, it was overt that there is neuro-alteration to the tissue. It showed increase contractility and loss of relaxation.

Histopathological Findings: Actinomycosis diverticulitis & abscess

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