Differentiating Hirschsprung's Disease from other Diseases

Hirschsprung's disease Microchapters
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1];Associate Editor(s)-in-Chief: Ahmed Younes M.B.B.CH [2]

Overview

Hirschsprung disease must be differentiated from other diseases that cause failure to pass meconium and abdominal distension in infants, such as meconium plug syndrome, small left colon syndrome and congenital hypothyroidism.

Differential Diagnosis

Hirschprung's disease must be differentiated from other diseases in infancy presenting with similar features such as failure to pass meconium, abdominal distention and non-bilious vomiting.

• Meconium plug syndrome
• Small left colon syndrome
• Distal small bowel /colonic atresia
• Meconium ileus and cystic fibrosis complex
• Congenital hypothyroidism