Mastoiditis pathophysiology
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Mastoiditis Microchapters |
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Diagnosis |
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Treatment |
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Case Studies |
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief:
Overview
- Because of the relation pass between the middle ear and mastoid air cells, bacteria may be transmitted to the mastoid air cells The inflammation and fluid and bacteria accumulation in mastoid cavities can cause periosteitis and then mastoid bony structure destruction. [1]
Pathogenesis
- Most common bacteria causing acute Mastoiditis Streptococcus pneumoniae, Streptococcus pyogenes, and Staphylococcus aureus
- The number of pneumococcal isolates and the percentage of isolates with high-level penicillin resistance from cultures taken from children with OM or mastoiditis for clinical indications have decreased following PCV13 use, largely due to decreases in serotype 19A isolates. [2]
References
- ↑ Lin HW, Shargorodsky J, Gopen Q (2010). "Clinical strategies for the management of acute mastoiditis in the pediatric population". Clin Pediatr (Phila). 49 (2): 110–5. doi:10.1177/0009922809344349. PMID 19734439.
- ↑ Kaplan SL, Center KJ, Barson WJ, Ling-Lin P, Romero JR, Bradley JS, Tan TQ, Hoffman JA, Peters TR, Gurtman A, Scott DA, Trammel J, Gruber WC, Hulten KG, Mason EO (2015). "Multicenter surveillance of Streptococcus pneumoniae isolates from middle ear and mastoid cultures in the 13-valent pneumococcal conjugate vaccine era". Clin. Infect. Dis. 60 (9): 1339–45. doi:10.1093/cid/civ067. PMID 25648240.