Echinococcosis medical therapy

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor-In-Chief: Cafer Zorkun, M.D., Ph.D. [2]

Overview

Both cystic echinococcosis and alveolar echinococcosis are complicated to treat, sometimes requiring extensive surgery and/or prolonged drug therapy. There are 3 options for the treatment of cystic echinococcosis:

• Anti-infective drug treatment
• Percutaneous treatment of the hydatid cysts with the PAIR (Puncture, Aspiration, Injection, Re-aspiration) technique;
• Surgery

Medical Therapy

Cystic echinococcosis stage 1 of less than 5 cm

• Preferred regimen: Albendazole 10 to 15 mg/kg per day q12
• Alternative regimen: Puncture, Aspiration, Injection, Re-aspiration (PAIR)

Cystic echinococcosis stage 1 of more than 5 cm

• Preferred regimen: Albendazole 10 to 15 mg/kg per day q12 and Puncture, Aspiration, Injection, Re-aspiration (PAIR)
• Alternative regimen: Puncture, Aspiration, Injection, Re-aspiration (PAIR)

Cystic echinococcosis stage 2 of any size

• Preferred regimen: Albendazole 10 to 15 mg/kg per day q12 + either modified catheterization or surgery
• Alternative regimen: Puncture, Aspiration, Injection, Re-aspiration (PAIR)

Cystic echinococcosis stage 3 of any size

• Preferred regimen: Albendazole 10 to 15 mg/kg per day q12 + either modified catheterization or surgery
• Alternative regimen: Puncture, Aspiration, Injection, Re-aspiration (PAIR)