Hypogonadism history and symptoms

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Ahmed Elsaiey, MBBCH [2]

Overview

History and symptoms

History is important in diagnosis of hypogonadism in both males and females. The onset of the symptoms and previous congenital gonadal anomalies should be known.

  • For both males and females:
    • History is important to know if there was any gonadal abnormality since birth or not. The onset of puberty should also be known.
    • Family history of delay of growth and development is also important.
  • For males:
    • History of any causes of testicular failure as radiation to testes, chemotherapy or drugs decreasing testosterone secretion.
  • For females:
    • Menstrual history is important and the date of menarche.
    • History of increased androgen secretion as ance and hirsutism.

Common symptoms in males

Symptoms of hypogonadism depends on the onset of the disease whether before puberty or after. In this table, the common symptoms of hypogonadism in both periods are enlisted.

Pre-pubertal Post-pubertal (Adult)

Signs and symptoms depend on the cause.

  • In female:
  • In male:
  • Lack of muscle and beard development during childhood
  • Growth problems
  • In adults: Sexual dysfunction, decreased beard and body hair, breast enlargement, muscle loss and infertility.
  • For hypogonadism caused by diseases from central nervous system, patients may show symptoms of other hormonal deficiencies.

Low Testosterone (Low T) symptoms include loss of energy, fatigue, loss of libido, muscle mass decline, decreased positive mood factors and an increased negative mood factors.

References

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