Hashimoto's thyroiditis history and symptoms
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Furqan M M. M.B.B.S[2]
Overview
The hallmark of Hashimoto's disease is hypothyroidism. A positive history of autoimmune diseases and certain drug use are suggestive of Hashimoto's disease. The most common symptoms of Hashimoto's thyroiditis include fatigue, constipation, and cold intolerance.
History
Patients with Hashimoto's thyroiditis usually have the history of other autoimmune diseases and family history of autoimmune diseases. Occasionally, there might be a history of certain drug use like interferon-alpha and monoclonal antibodies.
Symptoms
In many cases, Hashimoto's thyroiditis usually results in hypothyroidism, although, in its acute phase, it can cause a transient hyperthyroidism thyrotoxic state known as hashitoxicosis. Hypothyroidism resulting from Hashimoto's thyroiditis can cause these symptoms: [1][2]
General
- Fatigue
- Lethargy
- Myxedema
- Cold intolerance
- Weight gain
- Weight loss
- Migraines
- Puffy face
Localized symptoms
- Enlarged neck or presence of goiter
- Dysphonia (from involvement of the recurrent laryngeal nerve)
- Dyspnea (from the constriction of the trachea)
- Dysphagia (from impingement upon the esophagus)
- Small or shrunken thyroid gland (late in the disease)
Gastrointestinal system
Skin and appendages
Neuro-psychiatric system
- Depression
- Difficulty concentrating or thinking
- Mania
- Memory loss
- Panic attacks
Reproductive system
- Infertility
- Oligomenorrhea
- Menometrorrhagia
Musculoskeletal
- Joint stiffness
- Muscle cramps
References
- ↑ Ladenson P, Kim M. Thyroid. In: Goldman L and Ausiello D, eds. Goldman: Cecil Medicine. 23rd ed. Philadelphia, Pa:Saunders; 2007:chap 244.
- ↑ Caturegli P, De Remigis A, Rose NR (2014). "Hashimoto thyroiditis: clinical and diagnostic criteria". Autoimmun Rev. 13 (4–5): 391–7. doi:10.1016/j.autrev.2014.01.007. PMID 24434360.