Hypogonadism historical perspective
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Ahmed Elsaiey, MBBCH [2]
Overview
Hypogonadim was first reported by Dr. Maestre de San Juan in a case of small testes and loss of smelling sense in patient. Dr. Kallmann after that, in 1944, identified this syndrome and it was named based on his name. Dr. de Morsier reported various cases of hypogonadism with abscent olfactory bulbs in the 1950s.
Historical perspective
- In 1856, Dr. Maestre de San Juan was the first one to report a case combining small testes (hypogonadism) and loss of smelling sense in a patient.
- In 1944, Dr. Kallmann was the first to identify it as a syndrome which was named based on his name after then. He held a study showing the correlation between anosmia and hypogonadism in different families.[1]
- In the 1950s, Dr. de Morsier reported various cases of patients with hypogonadism and with abscent olfactory bulbs as well. After which, hypogonadism has been described as gonadotropin hormones deficiency.
References
- ↑ Dodé C, Hardelin JP (2009). "Kallmann syndrome". Eur J Hum Genet. 17 (2): 139–46. doi:10.1038/ejhg.2008.206. PMC 2986064. PMID 18985070.