Pituitary apoplexy risk factors

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] ; Associate Editor(s)-in-Chief: Akshun Kalia M.B.B.S.[2]

Overview

Common risk factors in the development of pituitary apoplexy include bleeding disorders, diabetes, head injury, radiation to the pituitary gland, use of a breathing machine, angiography and surgery.

Risk Factors

Common risk factors in the development of pituitary apoplexy include :

  • Bleeding disorders[1]
  • Diabetes
  • Head injury
  • Radiation to the pituitary gland
  • Use of a breathing machine
  • Angiography [1]
  • Surgery leading to hypotension and subsequent hypoperfusion of the pituitary gland.[1]
  • Pituitary stimulation with ACTH, TRH or GnRH analogues.
  • Pregnancy leads to increased pituitary volume secondary to lactotroph hyperplasia, which returns to normal six months post-partum. Estrogen induced increased blood flow to pituitary.

References

  1. 1.0 1.1 1.2 Briet C, Salenave S, Bonneville JF, Laws ER, Chanson P (2015). "Pituitary Apoplexy". Endocr. Rev. 36 (6): 622–45. doi:10.1210/er.2015-1042. PMID 26414232.

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