Hypoglycemia historical perspective
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Mohammed Abdelwahed M.D[2]
Overview
In 1922, Hypoglycemia was first discovered by James Collip when he was working on purifying insulin. Collip discovered that injection of a large dose of insulin into a rabbit, the rabbit got into a coma and died.
Historical Perspective[1]
- In 1869, Paul Langerhans discovers a collection of cells within the pancreas which have been called islets of Langerhans.
- In 1901, Eugene Opie discovers that destruction of islet cells results in diabetes mellitus.
- In 1921, a young orthopedic surgeon called Frederick Banting and Charles Best have discovered insulin in the pancreatic extracts of dogs. With help of James B. Collip and J.J.R. Macleod, They have developed insulin for human treatment. Nobel Prize was awarded to Banting and Macleod for this discovery.
- In 1922, Hypoglycemia was first discovered by James Collip when he was working on purifying insulin. He injected insulin into a rabbit and realized the reduction in blood glucose levels. Collip discovered that injection of a large dose of insulin, the rabbit got into a coma and died.
- Hypoglycemia is a Greek word means under-sweet blood.
References
- ↑ Rosenfeld L (2002). "Insulin: discovery and controversy". Clin Chem. 48 (12): 2270–88. PMID 12446492.