Pituitary apoplexy causes
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Akshun Kalia M.B.B.S.[2]
Overview
Pituitary apoplexy is most commonly caused by bleeding into the pituitary from a noncancerous tumor of the pituitary. When this bleeding occurs in a woman during or immediately after childbirth, it is called Sheehan syndrome.
Common causes
- The most common cause of pituitary apoplexy is pituitary adenoma (a benign tumor of pituitary gland).
- Coagulopathy, antiplatelet and thrombylytic therapy.[1]
- Surgery predisposing to hypotension. Any major surgery such as cardiovascular, abdominal or pelvic sugery may lead to significant blood loss and subsequent hypotension.
- Systemic hypertension: A number of cases of pituitary apoplexy have been reported in association with systemic hypertension.[2]
- Drugs: Dopamine receptor agonist, chlorpromazine, GnRH agonist and clomiphene.
- Estrogen therapy, pregnancy and post partum.
- Head injury
- Radiation therapy
- Hormonal stimulation of pituitary
- Pituitary surgery
References
- ↑ Baruah, ManashP; Ranabir, Salam (2011). "Pituitary apoplexy". Indian Journal of Endocrinology and Metabolism. 15 (7): 188. doi:10.4103/2230-8210.84862. ISSN 2230-8210.
- ↑ Rajasekaran S, Vanderpump M, Baldeweg S, Drake W, Reddy N, Lanyon M, Markey A, Plant G, Powell M, Sinha S, Wass J (2011). "UK guidelines for the management of pituitary apoplexy". Clin. Endocrinol. (Oxf). 74 (1): 9–20. doi:10.1111/j.1365-2265.2010.03913.x. PMID 21044119.