Pituitary apoplexy medical therapy
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Akshun Kalia M.B.B.S.[2]
Overview
The optimal therapy for pituitary apoplexy depends upon presentation of patient. Emphasis is on early hemodynamic stabilization of the patient, with evaluation for signs of pituitary hormones deficiency. Life threatening hypopituitarism must be treated with replacement of hormones.
Medical Therapy
Medical treatment consists of:
- Hemodynamic stability of the patient with evaluation for signs of pituitary hormones deficiency and electrolyte abnormalities.
- Most patients have life threatening hypopituitarism. Replace hormones with:
- High-dose corticosteroids
- Sex hormones (estrogen/testosterone)
- Thyroid hormone
Evidence is also growing for the need to replace growth hormone.