Ischemic colitis risk factors

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Mehrian Jafarizade, M.D [2]

Overview

Common Risk Factors

Risk factors associated with ischemic colitis listed below:^[1]

Cardiovascular and pulmonary

Atherosclerosis
Atrial fibrillation
Chronic obstructive pulmonary disease
Cerebrovascular disease
Congestive heart failure or ischemic heart disease
Congestive heart failure
Hypertension
Hypotension
Ischemic heart disease
Peripheral vascular disease
Shock

Gastrointestinal

Constipation
Diarrhea
Irritable bowel syndrome

Miscellaneous

Diabetes
Dyslipidemia
Rheumatoid arthritis
Systemic rheumatologic disorders
Hemodialysis
Thrombophilia including deficiencies of protein C, protein S, antithrombin III, and factor V Leiden mutation (21, 45, 50). catastrophic” variant of the antiphospholipid syndrome

Surgical history Abdominal surgery Aortic surgery

- Abdominal aortic aneurysm repair, particularly ruptured aneurysm forms
- Endovascular therapies
- Aortic catheterization

Cardiovascular surgery

- Cardiopulmonary bypass

Ileostomy Laparoscopy Prior colon carcinoma

Drugs:^[2]

Alosetron Digitalis Diuretics Cocaine Estrogens Danazol NSAIDs Tegaserod Vasoactive substances Paclitaxel and carboplatin Sumatriptan Antipsychotics Simvastatin Quetiapine Rizatriptan

Less Common Risk Factors

Renal disease ^[2] Extreme exercise Mesenteric arteriovenous fistula or malformation

References

↑ Hagihara PF, Ernst CB, Griffen WO (1979). "Incidence of ischemic colitis following abdominal aortic reconstruction". Surg Gynecol Obstet. 149 (4): 571–3.
↑ ^2.0 ^2.1 Longstreth GF, Yao JF (2010). "Diseases and drugs that increase risk of acute large bowel ischemia". Clin. Gastroenterol. Hepatol. 8 (1): 49–54. doi:10.1016/j.cgh.2009.09.006. PMID 19765672.

[pmid-1] Hagihara PF, Ernst CB, Griffen WO (1979). "Incidence of ischemic colitis following abdominal aortic reconstruction". Surg Gynecol Obstet. 149 (4): 571–3.

[pmid19765672-2] 2.0 ^2.1 Longstreth GF, Yao JF (2010). "Diseases and drugs that increase risk of acute large bowel ischemia". Clin. Gastroenterol. Hepatol. 8 (1): 49–54. doi:10.1016/j.cgh.2009.09.006. PMID 19765672.

[1]

[2]