Riedel's thyroiditis other diagnostic studies
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief:
Overview
- There are no other diagnostic studies associated with [disease name].
- [Diagnostic study] may be helpful in the diagnosis of [disease name]. Findings suggestive of/diagnostic of [disease name] include [finding 1], [finding 2], and [finding 3].
- Other diagnostic studies for [disease name] include [diagnostic study 1], which demonstrates [finding 1], [finding 2], and [finding 3], and [diagnostic study 2], which demonstrates [finding 1], [finding 2], and [finding 3].
Other Diagnostic Studies
- Other diagnostic studies for Riedel's thyroiditis include pathological and Immunohistochemical analysis.
Gross pathology
Gross pathology findings include:
- Pale thyroid mass
- No discernable tissue planes
Microscopic pathology
Microscopic pathology findings include:[1][2][3][4]
- Inflammatory cells infiltration
- Absence of giant cells, lymphoid follicles, oncocytes, or granulomas
- Fibrosis with hyalinization
- Extension of fibrosis outside the capsule
- Infiltration of plasma cells and lymphocytes in venular walls
Fine needle aspiration cytology
Fine needle aspiration cytology can lead to the misleading diagnosis due to fibrosis in Riedel thyroiditis. In most of the cases, it has no diagnostic value due to acellular or paucicellular smears.[5][6]Papi G, LiVolsi VA (2004). "Current concepts on Riedel thyroiditis". Am. J. Clin. Pathol. 121 Suppl: S50–63. PMID 15298150.
Immunohistochemical analysis
The immunohistochemical study in Riedel's thyroiditis is helpful to identify the inflammatory population of this form of thyroiditis. The findings include:[7][8][9][10]
- Predominance of T lymphocytes
- Presence of CD8+, CD4+ and plasma cells
- Presence of granulocytes and monocytes
- Strong positive stain to thyroglobulin
References
- ↑ BARTHOLOMEW LG, CAIN JC, WOOLNER LB, UTZ DC, FERRIS DO (1963). "Sclerosing cholangitis: its possible association with Riedel's struma and fibrous retroperitonitis. Report of two cases". N. Engl. J. Med. 269: 8–12. doi:10.1056/NEJM196307042690102. PMID 13969693.
- ↑ Rao CR, Ferguson GC, Kyle VN (1973). "Retroperitoneal fibrosis associated with Riedel's struma". Can Med Assoc J. 108 (8): 1019–21. PMC 1941367. PMID 4699273.
- ↑ Nazarian A, Pezzella L, Tseng A, Baldassarri S, Zurakowski D, Evans CH, Snyder BD (2010). "Application of structural rigidity analysis to assess fidelity of healed fractures in rat femurs with critical defects". Calcif. Tissue Int. 86 (5): 397–403. doi:10.1007/s00223-010-9353-4. PMC 4405879. PMID 20354683.
- ↑ Rabinovitch A, Pukel C, Baquerizo H (1988). "Interleukin-1 inhibits glucose-modulated insulin and glucagon secretion in rat islet monolayer cultures". Endocrinology. 122 (6): 2393–8. doi:10.1210/endo-122-6-2393. PMID 2453340.
- ↑ "Riedel's Thyroiditis in Multifocal Fibrosclerosis: CT and MR Imaging Findings | American Journal of Neuroradiology".
- ↑ Kini, Sudha (1987). Thyroid (Guides to Clinical Aspiration Biopsy). New York: Igaku-Shoin. ISBN 9780896401242.
- ↑ "Redirecting".
- ↑ Schwaegerle SM, Bauer TW, Esselstyn CB (1988). "Riedel's thyroiditis". Am. J. Clin. Pathol. 90 (6): 715–22. PMID 3057862.
- ↑ Weetman AP, McGregor AM (1994). "Autoimmune thyroid disease: further developments in our understanding". Endocr. Rev. 15 (6): 788–830. doi:10.1210/edrv-15-6-788. PMID 7705281.
- ↑ Papi G, Corrado S, Carapezzi C, De Gaetani C, Carani C (2003). "Riedel's thyroiditis and fibrous variant of Hashimoto's thyroiditis: a clinicopathological and immunohistochemical study". J. Endocrinol. Invest. 26 (5): 444–9. doi:10.1007/BF03345200. PMID 12906372.