Hirschsprung's disease risk factors
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Ahmed Younes M.B.B.CH [2]
Overview
The most potent risk factor for Hirschsprung's disease is a strong family history (multiple family members afflicted). Other risk factors include a family history of long segment disease and the proband being female.
Risk factors
The most potent risk factors for developing Hirschsprung's disease include:
- Having multiple family members affected by the disease[1]
- Family history of the long segment variant of the disease[2]
- Female proband
- Male gender
References
- ↑ Swenson O (2002). "Hirschsprung's disease: a review". Pediatrics. 109 (5): 914–8. PMID 11986456.
- ↑ Passarge E (1967). "The genetics of Hirschsprung's disease. Evidence for heterogeneous etiology and a study of sixty-three families". N. Engl. J. Med. 276 (3): 138–43. doi:10.1056/NEJM196701192760303. PMID 4224912.