Hirschsprung's disease history and symptoms
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]} ; Associate Editor(s)-in-Chief: Aditya Ganti M.B.B.S. [2]
Overview
Hirschsprung's disease is commonly diagnosed within the neonatal period. The cardinal symptoms of Hirschsprung's disease include abdominal distension, delayed passage of meconium (not passed until 24-48 hours after birth), and vomiting.[1][2]
History
- Delayed passage of meconium (not passed until 24-48 hours after birth).
- Ninety-four percent of Hirschsprung's disease cases are diagnosed before the patient reaches 5 years of age.
- History of longstanding recurrent constipation relieved by laxatives.
- History of progressive abdominal distention, colicky pain, or acute intestinal obstruction.[3]
Symptoms
The cardinal symptoms of Hirschsprung's disease include:
Other common symptoms that can be observed in patients with Hirschsprung's disease include:
- Constipation
- Malabsorption
- Poor weight gain
- Slow growth (0-5 years child)
- Watery diarrhea
Adult Hirschsprung's disease
- Hirschsprung's disease is uncommon in adolescence.
- It appears as an ultra-short segment disease.
- Presents as a long-standing constipation requiring frequent laxatives.
- Other symptoms may include:
References
- ↑ Stanescu AL, Liszewski MC, Lee EY, Phillips GS (2017). "Neonatal Gastrointestinal Emergencies: Step-by-Step Approach". Radiol. Clin. North Am. 55 (4): 717–739. doi:10.1016/j.rcl.2017.02.010. PMID 28601177.
- ↑ Das K, Mohanty S (2017). "Hirschsprung Disease - Current Diagnosis and Management". Indian J Pediatr. doi:10.1007/s12098-017-2371-8. PMID 28600660.
- ↑ Guderian R, Vargas J (1986). "Duffy blood group distribution and the incidence of malaria in Ecuador". Trans. R. Soc. Trop. Med. Hyg. 80 (1): 162–3. PMID 3726979.