Sheehan's syndrome diagnostic criteria

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Iqra Qamar M.D.[2]

Overview

Diagnosis is mostly clinical but following steps are required to make the established diagnosis.
- Detailed medical history
- Measurement of pituitary hormone levels in blood
- Pituitary hormone stimulation tests(insulin tolerance, chlorpromazine, metoclopramide and clomiphene citrate stimulation tests)^[1]^[2]
- Imaging(MRI preferred on CT)

Diagnosis is made on clinical basis with a recent/remote history of traumatic delivery or delivery complicated by hypotension.
Diagnosis is mostly clinical but following steps are required to make the established diagnosis.
- Detailed medical history
- Measurement of pituitary hormone levels in blood
- Pituitary hormone stimulation tests(insulin tolerance, chlorpromazine, metoclopramide and clomiphene citrate stimulation tests)^[1]^[2]
- Imaging(MRI preferred on CT)

↑ ^1.0 ^1.1 Cunningham SK, Moore A, McKenna TJ (1983). "Normal cortisol response to corticotropin in patients with secondary adrenal failure". Arch. Intern. Med. 143 (12): 2276–9. PMID 6316866.
↑ ^2.0 ^2.1 Grinspoon SK, Biller BM (1994). "Clinical review 62: Laboratory assessment of adrenal insufficiency". J. Clin. Endocrinol. Metab. 79 (4): 923–31. doi:10.1210/jcem.79.4.7962298. PMID 7962298.