Hypopituitarism historical perspective
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Ahmed Elsaiey, MBBCH [2]
Overview
Discovery of the hypopituitarism returns back to 1914 when Dr. Simmonds described the disease for the first time. The diagnosis has been based on the patients presentation only since then till 1950 when Dr. Yalow and Berson discobered the radioimmunoassay which helped in measurment the hormonal levels. Through the 20th and 21st centuries, causes of the hypopituitarism were being described.
Historical Perspective
- In 1914, Dr. Simmonds was the first one to describe the hypopituitarism. He described it as the inability of the pituitary gland to secrete hormones matching the organs need.[1]
- In 1950, Dr. Yalow and Berson discovered the radioimmunoassay which helped in measurement of the pituitary hormones after the diagnosis was only based on the signs and symptoms presented with the patients.[2]
- In 1973, combined stimulation tests of the hormones insulin, GnRH and TRH were performed for the first time to assess the pituitary gland funciton.[3]
- Through the 20th and 21st centuries, causes of the hypopituitarism were being described.
References
- ↑ Schneider HJ, Aimaretti G, Kreitschmann-Andermahr I, Stalla GK, Ghigo E (2007). "Hypopituitarism". Lancet. 369 (9571): 1461–70. doi:10.1016/S0140-6736(07)60673-4. PMID 17467517.
- ↑ Prozesky OW (1979). "Measles vaccination". S Afr Med J. 55 (7): 236. PMID 441860.
- ↑ Harsoulis P, Marshall JC, Kuku SF, Burke CW, London DR, Fraser TR (1973). "Combined test for assessment of anterior pituitary function". Br Med J. 4 (5888): 326–9. PMC 1587416. PMID 4202260.