Adrenocortical carcinoma history and symptoms
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Raviteja Guddeti, M.B.B.S. [2]Ahmad Al Maradni, M.D. [3]
Overview
Symptoms of adrenocortical carcinoma include symptoms of androgen, glucocorticoid, mineralocorticoid, or estrogen excess.
Common Symptoms
All patients with suspected adrenocortical carcinoma should be carefully evaluated for symptoms of hormonal syndromes.
This may include the following:
1- Symptoms of glucocorticoid excess include:
2- Symptoms of androgen excess symptoms (most readily noted among womens) include:
- Excess facial and body hair
- Acne
- Deepening of the voice
- Coarsening of facial features
- Cessation of menstruation
3- Symptoms of mineralcorticoid excess include:
4- Symptoms of estrogen excess (most readily noted in mens) include:
- Gynecomastia
- Decreased libido
- Impotence
5- symptoms of catecholamines excess has been reported in adrenocortical cancers:[1]
6- Other symptoms may include:[2]
- Abdominal lump
- Abdominal or back pain
- Abdominal fullness
References
- ↑ Richard Cote, Saul Suster, Lawrence Weiss, Noel Weidner (Editor). Modern Surgical Pathology (2 Volume Set). London: W B Saunders. ISBN 0-7216-7253-1.
- ↑ National Cancer Institute. Physician Data Query Database 2015.http://www.cancer.gov/types/adrenocortical/patient/adrenocortical-treatment-pdq#section/_1