Lymphadenopathy overview
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Raviteja Guddeti, M.B.B.S. [2]
Overview
Lymphadenopathy is a term meaning "disease of the lymph nodes." It is, however, almost synonymously used with "swollen/enlarged lymph nodes". When the infection is of the lymph nodes themselves, it is called lymphadenitis, but when the infection is of the lymph channels, it is called lymphangitis.
Pathophysiology
Lymph nodes are part of the immune system. As such, they are most readily palpable when fighting infections. Infections can either originate from the organs that they drain or primarily within the lymph node itself, referred to as lymphadenitis.
Epidemiology and Demographics
The estimated incidence of lymphadenopathy in children in the United States ranges from 35%- 45%. It is more common in the pediatric population. Race and gender have no predilection in lymphadenopathy incidence.
Diagnosis
Other Imaging Findings
Positron emission tomography (PET) is used to evaluate clinically diagnosed lymphadenopathy.
Treatment
Surgery
Surgical care involves open biopsy or aspiration of the lymph node and its removal.
Primary Prevention
Good general health and hygiene are helpful in the prevention of any infection.