Autoimmune polyendocrine syndrome historical perspective

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief:

Overview

The history associated with autoimmune polyendocrine syndrome is as below:^[1]^[2]

In 19th century physicians first focussed their attention on constellation of symptoms associated with autoimmune polyendocrine syndrome.
In 1855, Thomas Addison identified patients with Addison's disease who also appeared to have coexisting pernicious anemia.
In 1929, Thorpe and Handley first described the case of mucocutaneous candidiasis with glandular failure in a 4.5-year-old girl.
In 1956, Roitt and Doniach found that patients with Hashimoto's thyroiditis had circulating autoantibodies reacting with thyroid gland.
In 1981, Neufeld and colleagues categorised autoimmune polyendocrine syndrome into type 1 and type 2.

↑ Khalid, Nauman; Chhabra, Lovely; Ahmad, Sarah Aftab; Umer, Affan; Spodick, David H. (2015). "Autoimmune Polyglandular Syndrome Type 2 Complicated by Acute Adrenal Crisis and Pericardial Tamponade in the Setting of Normal Thyroid Function". Methodist DeBakey Cardiovascular Journal. 11 (4): 250–252. doi:10.14797/mdcj-11-4-250. ISSN 1947-6094.
↑ Betterle C, Dal Pra C, Mantero F, Zanchetta R (2002). "Autoimmune adrenal insufficiency and autoimmune polyendocrine syndromes: autoantibodies, autoantigens, and their applicability in diagnosis and disease prediction". Endocr. Rev. 23 (3): 327–64. doi:10.1210/edrv.23.3.0466. PMID 12050123.