Rabies diagnostic criteria
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief:
Overview
The diagnosis of [disease name] is made when at least [number] of the following [number] diagnostic criteria are met: [criterion 1], [criterion 2], [criterion 3], and [criterion 4].
OR
The diagnosis of [disease name] is based on the [criteria name] criteria, which include [criterion 1], [criterion 2], and [criterion 3].
OR
The diagnosis of [disease name] is based on the [definition name] definition, which includes [criterion 1], [criterion 2], and [criterion 3].
OR
There are no established criteria for the diagnosis of [disease name].
Diagnostic Criteria
The diagnosis of rabies is made on the basis of clinical and lab findings.
- Clinical diagnosis:
- A detailed medical history
- High index of suspicion (hydrophobia and aerophobia suggest encephalitic rabies)[1]
- Acute worsening of neurological functioning regardless of any previous history of animal bite or exposure
- Laboratory diagnosis:
- Virus-specific immunofluorescent staining of skin biopsy specimenssolation of virus from the saliva, or detection of anti-rabies antibodies in serum or cerebrospinal fluid (CSF)
References
- ↑ Venkatesan A, Tunkel AR, Bloch KC, Lauring AS, Sejvar J, Bitnun A, Stahl JP, Mailles A, Drebot M, Rupprecht CE, Yoder J, Cope JR, Wilson MR, Whitley RJ, Sullivan J, Granerod J, Jones C, Eastwood K, Ward KN, Durrheim DN, Solbrig MV, Guo-Dong L, Glaser CA (2013). "Case definitions, diagnostic algorithms, and priorities in encephalitis: consensus statement of the international encephalitis consortium". Clin. Infect. Dis. 57 (8): 1114–28. doi:10.1093/cid/cit458. PMC 3783060. PMID 23861361.