Myxedema coma diagnostic criteria
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] ; Associate Editor(s)-in-Chief: Aditya Ganti M.B.B.S. [2]
Overview
The diagnosis of myxedema coma is made when the three key diagnostic features of myxedema coma are present, which include altered mental status, hypothermia or absence of fever and a precipitating event such as cold exposure, infection, drugs.
Diagnostic criteria
The diagnosis of myxedema coma is made when the following three key diagnostic features are present, which include:[1]
- Altered mental status
- Hypothermia or absence of fever
- Precipitating event (cold exposure, infection, drugs)
Diagnostic scoring
- Traditionally different scores have been employed to assess the level of awareness or degree of sensory impairment such as the Glasgow scale and others such as the SOFA (Sequential Organ Failure Assessment) and APACHE II (Acute Physiology and Chronic Health Evaluation) assessing the severity of an illness and predict mortality.
- Diagnostic scoring of myxedema coma
- A score greater than 60 is highly suggestive / diagnosis of myxedema coma.
- A score between 29-59 is suggestive of coma risk myxedema.
- A score lower than 25 makes the diagnosis unlikely of myxedema coma.