Silent thyroiditis natural history, complications and prognosis

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Furqan M M. M.B.B.S[2]

Overview

Silent thyroiditis presents with the symptoms of thyrotoxicosis. It further leads to a euthyroid phase and eventually hypothyroid phase before the complete resolution of the disease. Complications may include hypothyroidism.

Natural history, complications, and prognosis

Natural history

Silent thyroiditis develops after a viral prodrome and presents as painful thyroid gland with symptoms of thyrotoxicosis. It further leads to an euthyroid phase and eventually hypothyroid phase before the complete resolution of the disease.[1][2][3][4]

Hyperthyroid stage

It follows the prodromal stage and includes the symptoms of thyrotoxicosis such as:

Euthyroid stage

Thyrotoxic stage is followed by a 1–3-week period of euthyroid phase.

Hypothyroid stage

The transient hypothyroid stage lasts for 6-12 months.

  • Rarely, the hypothyroid stage may persist for a longer duration.

Complications

Complications that can develop as a result of silent thyroiditis include:[1][5][4]

Prognosis

Prognosis of silent thyroiditis is usually good.

References

  1. ↑ 1.0 1.1 "Thyroiditis — NEJM".
  2. ↑ Samuels MH (2012). "Subacute, silent, and postpartum thyroiditis". Med. Clin. North Am. 96 (2): 223–33. doi:10.1016/j.mcna.2012.01.003. PMID 22443972.
  3. ↑ Walker P (1984). "Silent thyroiditis". Can Fam Physician. 30: 1337–9. PMC 2153523. PMID 21278944.
  4. ↑ 4.0 4.1 Díez JJ (1995). "[Silent thyroiditis and postpartum thyroiditis]". Aten Primaria (in Spanish; Castilian). 16 (3): 147–50. PMID 7647209.
  5. ↑ Noh JY (2012). "[Silent thyroiditis and subacute thyroiditis]". Nippon Rinsho (in Japanese). 70 (11): 1945–50. PMID 23214066.


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