Zenker's diverticulum causes
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief:
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Overview
Causes
ZD is caused by[1][2][3][4][5][5]
- Zenker's diverticulum also known as pharyngosophageal diverticulum.
- It is an acquired sac-like outpouching of the mucosa and submucosa layers originating from the pharyngoesophageal junction.
- Since it involves only the mucosa and submucosa it is a false diverticulum.
- Killian's dehiscence- pulsion false diverticulum occurring dorsally at the pharyngoesophageal wall bounded by the propulsive oblique inferior pharyngeal constrictor muscle and the transversal fibers of the cricopharyngeal muscle
- ZD occurs due to increased intraluminal pressure in the oropharynx during swallowing, against an inadequate relaxation of the cricopharyngeal muscle,
- A subsequent incomplete opening of the UES, causing the protrusion of the mucosa through an area of relative weakness at the dorsal pharyngoesophageal wall.
- ZD cause the disorder of the pharyngoesophageal phase of swallowing.
- The neuromuscular functions such as chewing, initiating the swallowing, and propulsion of the food from the oropharynx into the cervical esophagus.
References
- ↑ "Zenker's diverticula: pathophysiology, clinical presentation, and flexible endoscopic management. - PubMed - NCBI".
- ↑ "Cause and treatment of epiphrenic diverticula. - PubMed - NCBI".
- ↑ "Zenker's diverticulum: exploring treatment options. - PubMed - NCBI".
- ↑ "Zenker's diverticulum. - PubMed - NCBI".
- ↑ 5.0 5.1 "[The physiopathological basis for Zenker's diverticulum]. - PubMed - NCBI".