Ganglioglioma MRI

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]Associate Editor(s)-in-Chief: Sujit Routray, M.D. [2]

Overview

On MRI of the brain, ganglioglioma is characterized by iso- to hypointense solid component on T1, variable contrast enhancement of solid component on T1 C+ (Gd), hyperintense solid component and variable signal in cystic component on T2, and calcification on T2 (GE/SWI). On MRI of the spinal cord, ganglioglioma is characterized by mixed signal intensity on T1-weighted images, high intensity on T2, patchy enhancement on T1 C+ (Gd), and calcification with low signal blooming on gradient echo.

MRI

• 1. Brain MRI scan is helpful in the diagnosis of cerebral ganglioglioma. On MRI of the brain, ganglioglioma is characterized by:

MRI Component	Features
T1​	Solid component iso- to hypointense
T1 C+ (Gd)	Solid component variable contrast enhancement
T2	Hyperintense solid component Variable signal in the cystic component Peritumoral flair/T2 edema is rare
T2 (GE/SWI)	Calcified areas shows blooming signal loss

• 2. MRI scan of the spinal cord is helpful in the diagnosis of spinal cord ganglioglioma. On MRI of the spinal cord, ganglioglioma is characterized by:

MRI Component	Features
T1​	Mixed signal intensity
T1 C+ (Gd)	Patchy or no enhancement
T2	High intensity Surrounding edema is rare
Gradient echo	Calcification is common, low signal with blooming

References

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