Gallstone disease causes

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Luke Rusowicz-Orazem, B.S. Hadeel Maksoud M.D.[2]

Overview

Common causes of gallstone disease include drug side effects and hematological conditions. Diagnosis of cirrhosis as a life-threatening cause of gallstone disease.

Causes

Life Threatening Causes

• Biliary cirrhosis
• Cystic fibrosis
• Liver cirrhosis

Common Causes

• Aging
• Clofibrate
• Combined oral contraceptive pill
• Diabetes
• Fasting
• Hemolytic anemia
• Inflammatory bowel disease
• Obesity
• Pregnancy

Causes by Organ System

Cardiovascular	Williams syndrome
Chemical / poisoning	No underlying causes
Dermatologic	No underlying causes
Drug Side Effect	Atazanavir, Ceftriaxone, Clofibrate, Combined oral contraceptive pill, Febuxostat, Hormonal contraception, Lanreotide, Leflunomide, Oxcarbazepine, Pasireotide, Pergolide, Pramipexole, Proton pump inhibitors, Rilpivirine, Somatostatin, Teduglutide, Tiagabine, Zonisamide
Ear Nose Throat	No underlying causes
Endocrine	Diabetes, Somatostatinoma
Environmental	No underlying causes
Gastroenterologic	Crohn's disease, Liver cirrhosis, Ulcerative colitis, Cystic fibrosis
Genetic	Erythropoietic protoporphyria, Hemochromatosis, Hereditary spherocytosis, Williams Syndrome , Hemoglobin E disease, Hemolytic anemia, Sickle cell disease, Cystic fibrosis
Hematologic	Hemoglobin E disease, Hemolytic anemia, Sickle cell disease, Hemochromatosis, Hereditary spherocytosis, Erythropoietic protoporphyria
Iatrogenic	Long term intravenous nutrition, Weight loss surgery
Infectious Disease	Clonorchiasis, Infection in the gallbladder
Musculoskeletal / Ortho	No underlying causes
Neurologic	Williams syndrome
Nutritional / Metabolic	Hypercalcaemia, Low-fibre, high-cholesterol diets, Hemochromatosis, Williams syndrome, Erythropoietic protoporphyria, Dieting, Fasting
Obstetric/Gynecologic	Pregnancy
Oncologic	Somatostatinoma
Opthalmologic	No underlying causes
Overdose / Toxicity	Ceftriaxone, Clofibrate, Combined oral contraceptive pill, Hormonal contraception, Lanreotide, Pasireotide, Proton pump inhibitors, Somatostatin
Psychiatric	No underlying causes
Pulmonary	Cystic fibrosis
Renal / Electrolyte	No underlying causes
Rheum / Immune / Allergy	Ulcerative colitis, Crohn's disease
Sexual	Cystic fibrosis
Trauma	No underlying causes
Urologic	No underlying causes
Dental	No underlying causes
Miscellaneous	Aging, Dieting, Fasting, Obesity, Rapid weight loss

Causes in Alphabetical Order

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