Spontaneous coronary artery dissection differential diagnosis
Spontaneous Coronary Artery Dissection Microchapters |
Differentiating Spontaneous coronary artery dissection from other Diseases |
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Arzu Kalayci, M.D. [2]
Synonyms and keywords: SCAD
Overview
Differential Diagnosis
Albeit an infrequent condition, spontaneous coronary artery dissection (SCAD) should be included in the differential diagnosis of acute coronary syndrome, particularly among young women who have risk factors such as vasculopathy, pregnancy, connective tissue disorder, systemic inflammation, strenuous exercise, emotional stress, or recreational drug use. Although intracoronary imaging such as intravascular ultrasound (IVUS) and optical coherence tomography (OCT) may be required for establishing a definitive diagnosis of SCAD, demographic and angiographic characteristics may be useful in differentiating SCAD from other causes of myocardial ischemia.
Demographic characteristics that raise the index of suspicion for SCAD include:[1]
- Myocardial infarction in young women (age ≤50)
- Absence of traditional cardiovascular risk factors
- Little or no evidence of coronary atherosclerosis
- Peripartum state
- History of fibromuscular dysplasia
- History of connective tissue disorder or systemic inflammatory disorder:
Angiographic characteristics
References
- ↑ Saw J (2014). "Coronary angiogram classification of spontaneous coronary artery dissection". Catheter Cardiovasc Interv. 84 (7): 1115–22. doi:10.1002/ccd.25293. PMID 24227590.