Portal vein thrombosis epidemiology and demographics

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Farima Kahe M.D. [2]

Overview

Epidemiology and Demographics

Incidence

  • The incidence of portal vein thrombosis in cirrhotic patients is unknown.[1]

Prevalence

  • The prevalence of portal vein thrombosis is approximately 5000-10,000 per 100,000 in overall cases of portal hypertension in developed counties and 40,000 per 100,000 in developing countries.[1][2]
  • The prevalence of portal vein thrombosis is less than 1000 per 100,000 in patients with compensated cirrhosis, but is 8000-25000 per 100,000 in patients who are candidates for liver transplantation.[3][4]

Mortality rate

  • The overall mortality rate of portal vein thrombosis is less than 10% except for patients with malignancy or cirrhosis.[1]
  • The mortality rate of portal vein thrombosis in patients with malignancy or cirrhosis about 26%.[5]

Age

  • Patients of all age groups may develop [disease name].
  • The incidence of [disease name] increases with age; the median age at diagnosis is [#] years.
  • [Disease name] commonly affects individuals younger than/older than [number of years] years of age.
  • [Chronic disease name] is usually first diagnosed among [age group].
  • [Acute disease name] commonly affects [age group].

Race

  • There is no racial predilection to [disease name].
  • [Disease name] usually affects individuals of the [race 1] race. [Race 2] individuals are less likely to develop [disease name].

Gender

  • [Disease name] affects men and women equally.
  • [Gender 1] are more commonly affected by [disease name] than [gender 2]. The [gender 1] to [gender 2] ratio is approximately [number > 1] to 1.

Region

  • The majority of [disease name] cases are reported in [geographical region].
  • [Disease name] is a common/rare disease that tends to affect [patient population 1] and [patient population 2].

Developed Countries

Developing Countries

References

  1. 1.0 1.1 1.2 Ponziani FR, Zocco MA, Campanale C, Rinninella E, Tortora A, Di Maurizio L, Bombardieri G, De Cristofaro R, De Gaetano AM, Landolfi R, Gasbarrini A (2010). "Portal vein thrombosis: insight into physiopathology, diagnosis, and treatment". World J. Gastroenterol. 16 (2): 143–55. PMC 2806552. PMID 20066733.
  2. Ogren M, Bergqvist D, Björck M, Acosta S, Eriksson H, Sternby NH (2006). "Portal vein thrombosis: prevalence, patient characteristics and lifetime risk: a population study based on 23,796 consecutive autopsies". World J. Gastroenterol. 12 (13): 2115–9. PMC 4087695. PMID 16610067.
  3. Okuda K, Ohnishi K, Kimura K, Matsutani S, Sumida M, Goto N, Musha H, Takashi M, Suzuki N, Shinagawa T (1985). "Incidence of portal vein thrombosis in liver cirrhosis. An angiographic study in 708 patients". Gastroenterology. 89 (2): 279–86. PMID 4007419.
  4. Francoz C, Belghiti J, Vilgrain V, Sommacale D, Paradis V, Condat B, Denninger MH, Sauvanet A, Valla D, Durand F (2005). "Splanchnic vein thrombosis in candidates for liver transplantation: usefulness of screening and anticoagulation". Gut. 54 (5): 691–7. doi:10.1136/gut.2004.042796. PMC 1774501. PMID 15831918.
  5. Chawla YK, Bodh V (2015). "Portal vein thrombosis". J Clin Exp Hepatol. 5 (1): 22–40. doi:10.1016/j.jceh.2014.12.008. PMC 4415192. PMID 25941431.

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