CRTC2
CREB regulated transcription coactivator 2 | |||||
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Identifiers | |||||
Symbols | CRTC2 ; RP11-422P24.6; TORC2 | ||||
External IDs | Template:OMIM5 Template:MGI HomoloGene: 18765 | ||||
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Orthologs | |||||
Template:GNF Ortholog box | |||||
Species | Human | Mouse | |||
Entrez | n/a | n/a | |||
Ensembl | n/a | n/a | |||
UniProt | n/a | n/a | |||
RefSeq (mRNA) | n/a | n/a | |||
RefSeq (protein) | n/a | n/a | |||
Location (UCSC) | n/a | n/a | |||
PubMed search | n/a | n/a |
CREB regulated transcription coactivator 2, also known as CRTC2, is a human gene.[1]
References
Further reading
- Maruyama K, Sugano S (1994). "Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides". Gene. 138 (1–2): 171–4. PMID 8125298.
- Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K; et al. (1997). "Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library". Gene. 200 (1–2): 149–56. PMID 9373149.
- Strausberg RL, Feingold EA, Grouse LH; et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMID 12477932.
- Iourgenko V, Zhang W, Mickanin C; et al. (2003). "Identification of a family of cAMP response element-binding protein coactivators by genome-scale functional analysis in mammalian cells". Proc. Natl. Acad. Sci. U.S.A. 100 (21): 12147–52. doi:10.1073/pnas.1932773100. PMID 14506290.
- Conkright MD, Canettieri G, Screaton R; et al. (2003). "TORCs: transducers of regulated CREB activity". Mol. Cell. 12 (2): 413–23. PMID 14536081.
- Ota T, Suzuki Y, Nishikawa T; et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
- Jin J, Smith FD, Stark C; et al. (2004). "Proteomic, functional, and domain-based analysis of in vivo 14-3-3 binding proteins involved in cytoskeletal regulation and cellular organization". Curr. Biol. 14 (16): 1436–50. doi:10.1016/j.cub.2004.07.051. PMID 15324660.
- Screaton RA, Conkright MD, Katoh Y; et al. (2004). "The CREB coactivator TORC2 functions as a calcium- and cAMP-sensitive coincidence detector". Cell. 119 (1): 61–74. doi:10.1016/j.cell.2004.09.015. PMID 15454081.
- Al-Hakim AK, Göransson O, Deak M; et al. (2006). "14-3-3 cooperates with LKB1 to regulate the activity and localization of QSK and SIK". J. Cell. Sci. 118 (Pt 23): 5661–73. doi:10.1242/jcs.02670. PMID 16306228.
- Siu YT, Chin KT, Siu KL; et al. (2006). "TORC1 and TORC2 coactivators are required for tax activation of the human T-cell leukemia virus type 1 long terminal repeats". J. Virol. 80 (14): 7052–9. doi:10.1128/JVI.00103-06. PMID 16809310.
- Wu Z, Huang X, Feng Y; et al. (2006). "Transducer of regulated CREB-binding proteins (TORCs) induce PGC-1alpha transcription and mitochondrial biogenesis in muscle cells". Proc. Natl. Acad. Sci. U.S.A. 103 (39): 14379–84. doi:10.1073/pnas.0606714103. PMID 16980408.
- Yang Q, Inoki K, Ikenoue T, Guan KL (2006). "Identification of Sin1 as an essential TORC2 component required for complex formation and kinase activity". Genes Dev. 20 (20): 2820–32. doi:10.1101/gad.1461206. PMID 17043309.
- Ewing RM, Chu P, Elisma F; et al. (2007). "Large-scale mapping of human protein-protein interactions by mass spectrometry". Mol. Syst. Biol. 3: 89. doi:10.1038/msb4100134. PMID 17353931.
- Ravnskjaer K, Kester H, Liu Y; et al. (2007). "Cooperative interactions between CBP and TORC2 confer selectivity to CREB target gene expression". EMBO J. 26 (12): 2880–9. doi:10.1038/sj.emboj.7601715. PMID 17476304.
- Kuraishy AI, French SW, Sherman M; et al. (2007). "TORC2 regulates germinal center repression of the TCL1 oncoprotein to promote B cell development and inhibit transformation". Proc. Natl. Acad. Sci. U.S.A. 104 (24): 10175–80. doi:10.1073/pnas.0704170104. PMID 17548807.
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