NRD1

Nardilysin (N-arginine dibasic convertase)
Identifiers
Symbols	NRD1 ; hNRD1; hNRD2
External IDs	Template:OMIM5 Template:MGI HomoloGene: 68260
Gene ontology Molecular function Template:GNF GO Template:GNF GO Template:GNF GO Template:GNF GO Template:GNF GO Cellular component Template:GNF GO Template:GNF GO Biological process Template:GNF GO Template:GNF GO Template:GNF GO Template:GNF GO
RNA expression pattern
File:PBB GE NRD1 208709 s at tn.png
More reference expression data
Orthologs
Template:GNF Ortholog box
Species	Human	Mouse
Entrez	n/a	n/a
Ensembl	n/a	n/a
UniProt	n/a	n/a
RefSeq (mRNA)	n/a	n/a
RefSeq (protein)	n/a	n/a
Location (UCSC)	n/a	n/a
PubMed search	n/a	n/a

Nardilysin (N-arginine dibasic convertase), also known as NRD1, is a human gene.

Further reading

• Seidah NG, Prat A (2003). "Precursor convertases in the secretory pathway, cytosol and extracellular milieu". Essays Biochem. 38: 79–94. PMID 12463163.
• Hospital V, Prat A (2005). "Nardilysin, a basic residues specific metallopeptidase that mediates cell migration and proliferation". Protein Pept. Lett. 11 (5): 501–8. PMID 15544571.
• Fumagalli P, Accarino M, Egeo A; et al. (1998). "Human NRD convertase: a highly conserved metalloendopeptidase expressed at specific sites during development and in adult tissues". Genomics. 47 (2): 238–45. doi:10.1006/geno.1997.5078. PMID 9479496.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Hospital V, Prat A, Joulie C; et al. (1998). "Human and rat testis express two mRNA species encoding variants of NRD convertase, a metalloendopeptidase of the insulinase family". Biochem. J. 327 ( Pt 3): 773–9. PMID 9581555.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Winter AG, Pierotti AR (2001). "Gene expression of the dibasic-pair cleaving enzyme NRD convertase (N-arginine dibasic convertase) is differentially regulated in the GH3 pituitary and Mat-Lu prostate cell lines". Biochem. J. 351 Pt 3: 755–64. PMID 11042131.
• Nishi E, Prat A, Hospital V; et al. (2001). "N-arginine dibasic convertase is a specific receptor for heparin-binding EGF-like growth factor that mediates cell migration". EMBO J. 20 (13): 3342–50. doi:10.1093/emboj/20.13.3342. PMID 11432822.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Ma Z, Csuhai E, Chow KM, Hersh LB (2001). "Expression of the acidic stretch of nardilysin as a functional binding domain". Biochemistry. 40 (31): 9447–52. PMID 11478915.CS1 maint: Multiple names: authors list (link)
• Hospital V, Nishi E, Klagsbrun M; et al. (2003). "The metalloendopeptidase nardilysin (NRDc) is potently inhibited by heparin-binding epidermal growth factor-like growth factor (HB-EGF)". Biochem. J. 367 (Pt 1): 229–38. doi:10.1042/BJ20020822. PMID 12095415.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Strausberg RL, Feingold EA, Grouse LH; et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMID 12477932.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Chow KM, Oakley O, Goodman J; et al. (2003). "Nardilysin cleaves peptides at monobasic sites". Biochemistry. 42 (7): 2239–44. doi:10.1021/bi027178d. PMID 12590613.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Ota T, Suzuki Y, Nishikawa T; et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Gerhard DS, Wagner L, Feingold EA; et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMID 15489334.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Kimura K, Wakamatsu A, Suzuki Y; et al. (2006). "Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes". Genome Res. 16 (1): 55–65. doi:10.1101/gr.4039406. PMID 16344560.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Gregory SG, Barlow KF, McLay KE; et al. (2006). "The DNA sequence and biological annotation of human chromosome 1". Nature. 441 (7091): 315–21. doi:10.1038/nature04727. PMID 16710414.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Nishi E, Hiraoka Y, Yoshida K; et al. (2006). "Nardilysin enhances ectodomain shedding of heparin-binding epidermal growth factor-like growth factor through activation of tumor necrosis factor-alpha-converting enzyme". J. Biol. Chem. 281 (41): 31164–72. doi:10.1074/jbc.M601316200. PMID 16923819.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Bernstein HG, Stricker R, Dobrowolny H; et al. (2007). "Histochemical evidence for wide expression of the metalloendopeptidase nardilysin in human brain neurons". Neuroscience. 146 (4): 1513–23. doi:10.1016/j.neuroscience.2007.02.057. PMID 17442499.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)