SMG5

Smg-5 homolog, nonsense mediated mRNA decay factor (C. elegans)
File:PBB Protein SMG5 image.jpg PDB rendering based on 2hwy.
Available structures PDB Ortholog search: Template:Homologene2PDBe PDBe, Template:Homologene2uniprot RCSB List of PDB id codes 2hwy​
Identifiers
Symbols	SMG5 ; EST1B; FLJ34864; KIAA1089; LPTS-RP1; LPTSRP1; RP11-54H19.7; SMG-5
External IDs	Template:MGI HomoloGene: 9095
Gene ontology Molecular function Template:GNF GO Template:GNF GO Cellular component Template:GNF GO Template:GNF GO Biological process Template:GNF GO Template:GNF GO Template:GNF GO
RNA expression pattern
File:PBB GE SMG5 212147 at tn.png
File:PBB GE SMG5 34868 at tn.png
More reference expression data
Orthologs
Template:GNF Ortholog box
Species	Human	Mouse
Entrez	n/a	n/a
Ensembl	n/a	n/a
UniProt	n/a	n/a
RefSeq (mRNA)	n/a	n/a
RefSeq (protein)	n/a	n/a
Location (UCSC)	n/a	n/a
PubMed search	n/a	n/a

Smg-5 homolog, nonsense mediated mRNA decay factor (C. elegans), also known as SMG5, is a human gene.

Further reading

• Nakajima D, Okazaki N, Yamakawa H; et al. (2003). "Construction of expression-ready cDNA clones for KIAA genes: manual curation of 330 KIAA cDNA clones". DNA Res. 9 (3): 99–106. PMID 12168954.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Kikuno R, Nagase T, Ishikawa K; et al. (1999). "Prediction of the coding sequences of unidentified human genes. XIV. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro". DNA Res. 6 (3): 197–205. PMID 10470851.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Strausberg RL, Feingold EA, Grouse LH; et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMID 12477932.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Reichenbach P, Höss M, Azzalin CM; et al. (2003). "A human homolog of yeast Est1 associates with telomerase and uncaps chromosome ends when overexpressed". Curr. Biol. 13 (7): 568–74. PMID 12676087.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Snow BE, Erdmann N, Cruickshank J; et al. (2004). "Functional conservation of the telomerase protein Est1p in humans". Curr. Biol. 13 (8): 698–704. PMID 12699629.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Ohnishi T, Yamashita A, Kashima I; et al. (2004). "Phosphorylation of hUPF1 induces formation of mRNA surveillance complexes containing hSMG-5 and hSMG-7". Mol. Cell. 12 (5): 1187–200. PMID 14636577.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Ota T, Suzuki Y, Nishikawa T; et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Gerhard DS, Wagner L, Feingold EA; et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMID 15489334.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Unterholzner L, Izaurralde E (2005). "SMG7 acts as a molecular link between mRNA surveillance and mRNA decay". Mol. Cell. 16 (4): 587–96. doi:10.1016/j.molcel.2004.10.013. PMID 15546618.
• Fukuhara N, Ebert J, Unterholzner L; et al. (2005). "SMG7 is a 14-3-3-like adaptor in the nonsense-mediated mRNA decay pathway". Mol. Cell. 17 (4): 537–47. doi:10.1016/j.molcel.2005.01.010. PMID 15721257.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Azzalin CM, Lingner J (2006). "The human RNA surveillance factor UPF1 is required for S phase progression and genome stability". Curr. Biol. 16 (4): 433–9. doi:10.1016/j.cub.2006.01.018. PMID 16488880.
• Gregory SG, Barlow KF, McLay KE; et al. (2006). "The DNA sequence and biological annotation of human chromosome 1". Nature. 441 (7091): 315–21. doi:10.1038/nature04727. PMID 16710414.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Lee H, Sengupta N, Villagra A; et al. (2006). "Histone deacetylase 8 safeguards the human ever-shorter telomeres 1B (hEST1B) protein from ubiquitin-mediated degradation". Mol. Cell. Biol. 26 (14): 5259–69. doi:10.1128/MCB.01971-05. PMID 16809764.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Glavan F, Behm-Ansmant I, Izaurralde E, Conti E (2007). "Structures of the PIN domains of SMG6 and SMG5 reveal a nuclease within the mRNA surveillance complex". EMBO J. 25 (21): 5117–25. doi:10.1038/sj.emboj.7601377. PMID 17053788.CS1 maint: Multiple names: authors list (link)