PIK3R3

Phosphoinositide-3-kinase, regulatory subunit 3 (p55, gamma)
File:PBB Protein PIK3R3 image.jpg PDB rendering based on 2pna.
Available structures PDB Ortholog search: Template:Homologene2PDBe PDBe, Template:Homologene2uniprot RCSB List of PDB id codes 2pna​, 2pnb​
Identifiers
Symbols	PIK3R3 ; DKFZp686P05226; FLJ41892; p55-GAMMA
External IDs	Template:OMIM5 Template:MGI HomoloGene: 2690
Gene ontology Molecular function Template:GNF GO Template:GNF GO Template:GNF GO Template:GNF GO Template:GNF GO Cellular component Template:GNF GO Biological process Template:GNF GO Template:GNF GO
RNA expression pattern
File:PBB GE PIK3R3 202743 at tn.png
File:PBB GE PIK3R3 211580 s at tn.png
More reference expression data
Orthologs
Template:GNF Ortholog box
Species	Human	Mouse
Entrez	n/a	n/a
Ensembl	n/a	n/a
UniProt	n/a	n/a
RefSeq (mRNA)	n/a	n/a
RefSeq (protein)	n/a	n/a
Location (UCSC)	n/a	n/a
PubMed search	n/a	n/a

Phosphoinositide-3-kinase, regulatory subunit 3 (p55, gamma), also known as PIK3R3, is a human gene.

Further reading

• Pons S, Asano T, Glasheen E; et al. (1995). "The structure and function of p55PIK reveal a new regulatory subunit for phosphatidylinositol 3-kinase". Mol. Cell. Biol. 15 (8): 4453–65. PMID 7542745.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Andersson B, Wentland MA, Ricafrente JY; et al. (1996). "A "double adaptor" method for improved shotgun library construction". Anal. Biochem. 236 (1): 107–13. doi:10.1006/abio.1996.0138. PMID 8619474.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Tuscano JM, Engel P, Tedder TF; et al. (1996). "Involvement of p72syk kinase, p53/56lyn kinase and phosphatidyl inositol-3 kinase in signal transduction via the human B lymphocyte antigen CD22". Eur. J. Immunol. 26 (6): 1246–52. PMID 8647200.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Takahashi-Tezuka M, Hibi M, Fujitani Y; et al. (1997). "Tec tyrosine kinase links the cytokine receptors to PI-3 kinase probably through JAK". Oncogene. 14 (19): 2273–82. doi:10.1038/sj.onc.1201071. PMID 9178903.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Mothe I, Delahaye L, Filloux C; et al. (1998). "Interaction of wild type and dominant-negative p55PIK regulatory subunit of phosphatidylinositol 3-kinase with insulin-like growth factor-1 signaling proteins". Mol. Endocrinol. 11 (13): 1911–23. PMID 9415396.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Dey BR, Furlanetto RW, Nissley SP (1998). "Cloning of human p55 gamma, a regulatory subunit of phosphatidylinositol 3-kinase, by a yeast two-hybrid library screen with the insulin-like growth factor-I receptor". Gene. 209 (1–2): 175–83. PMID 9524259.CS1 maint: Multiple names: authors list (link)
• Xia X, Serrero G (1999). "Multiple forms of p55PIK, a regulatory subunit of phosphoinositide 3-kinase, are generated by alternative initiation of translation". Biochem. J. 341 ( Pt 3): 831–7. PMID 10417350.
• Inukai K, Funaki M, Anai M; et al. (2001). "Five isoforms of the phosphatidylinositol 3-kinase regulatory subunit exhibit different associations with receptor tyrosine kinases and their tyrosine phosphorylations". FEBS Lett. 490 (1–2): 32–8. PMID 11172806.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Hafizi S, Alindri F, Karlsson R, Dahlbäck B (2003). "Interaction of Axl receptor tyrosine kinase with C1-TEN, a novel C1 domain-containing protein with homology to tensin". Biochem. Biophys. Res. Commun. 299 (5): 793–800. PMID 12470648.CS1 maint: Multiple names: authors list (link)
• Strausberg RL, Feingold EA, Grouse LH; et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMID 12477932.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Xia X, Cheng A, Akinmade D, Hamburger AW (2003). "The N-terminal 24 amino acids of the p55 gamma regulatory subunit of phosphoinositide 3-kinase binds Rb and induces cell cycle arrest". Mol. Cell. Biol. 23 (5): 1717–25. PMID 12588990.CS1 maint: Multiple names: authors list (link)
• Ota T, Suzuki Y, Nishikawa T; et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Rual JF, Venkatesan K, Hao T; et al. (2005). "Towards a proteome-scale map of the human protein-protein interaction network". Nature. 437 (7062): 1173–8. doi:10.1038/nature04209. PMID 16189514.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Soroceanu L, Kharbanda S, Chen R; et al. (2007). "Identification of IGF2 signaling through phosphoinositide-3-kinase regulatory subunit 3 as a growth-promoting axis in glioblastoma". Proc. Natl. Acad. Sci. U.S.A. 104 (9): 3466–71. doi:10.1073/pnas.0611271104. PMID 17360667.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Kallin A, Johannessen LE, Cani PD; et al. (2007). "SREBP-1 regulates the expression of heme oxygenase 1 and the phosphatidylinositol-3 kinase regulatory subunit p55 gamma". J. Lipid Res. 48 (7): 1628–36. doi:10.1194/jlr.M700136-JLR200. PMID 17452746.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)