VAMP4

Vesicle-associated membrane protein 4
File:PBB Protein VAMP4 image.jpg PDB rendering based on 2nps.
Available structures PDB Ortholog search: Template:Homologene2PDBe PDBe, Template:Homologene2uniprot RCSB List of PDB id codes 2nps​
Identifiers
Symbols	VAMP4 ; VAMP24
External IDs	Template:OMIM5 Template:MGI HomoloGene: 37847
Gene ontology Cellular component Template:GNF GO Template:GNF GO Template:GNF GO Template:GNF GO Template:GNF GO Biological process Template:GNF GO Template:GNF GO
RNA expression pattern
File:PBB GE VAMP4 207350 s at tn.png
File:PBB GE VAMP4 213480 at tn.png
More reference expression data
Orthologs
Template:GNF Ortholog box
Species	Human	Mouse
Entrez	n/a	n/a
Ensembl	n/a	n/a
UniProt	n/a	n/a
RefSeq (mRNA)	n/a	n/a
RefSeq (protein)	n/a	n/a
Location (UCSC)	n/a	n/a
PubMed search	n/a	n/a

Vesicle-associated membrane protein 4, also known as VAMP4, is a human gene.

Synaptobrevins/VAMPs, syntaxins, and the 25-kD synaptosomal-associated protein SNAP25 are the main components of a protein complex involved in the docking and/or fusion of synaptic vesicles with the presynaptic membrane. The protein encoded by this gene is a member of the vesicle-associated membrane protein (VAMP)/synaptobrevin family. This protein may play a role in trans-Golgi network-to-endosome transport.

Further reading

• Andersson B, Wentland MA, Ricafrente JY; et al. (1996). "A "double adaptor" method for improved shotgun library construction". Anal. Biochem. 236 (1): 107–13. doi:10.1006/abio.1996.0138. PMID 8619474.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Yu W, Andersson B, Worley KC; et al. (1997). "Large-scale concatenation cDNA sequencing". Genome Res. 7 (4): 353–8. PMID 9110174.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Advani RJ, Bae HR, Bock JB; et al. (1998). "Seven novel mammalian SNARE proteins localize to distinct membrane compartments". J. Biol. Chem. 273 (17): 10317–24. PMID 9553086.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Steegmaier M, Klumperman J, Foletti DL; et al. (1999). "Vesicle-associated membrane protein 4 is implicated in trans-Golgi network vesicle trafficking". Mol. Biol. Cell. 10 (6): 1957–72. PMID 10359608.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Scales SJ, Chen YA, Yoo BY; et al. (2000). "SNAREs contribute to the specificity of membrane fusion". Neuron. 26 (2): 457–64. PMID 10839363.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Peden AA, Park GY, Scheller RH (2002). "The Di-leucine motif of vesicle-associated membrane protein 4 is required for its localization and AP-1 binding". J. Biol. Chem. 276 (52): 49183–7. doi:10.1074/jbc.M106646200. PMID 11598115.CS1 maint: Multiple names: authors list (link)
• Mallard F, Tang BL, Galli T; et al. (2002). "Early/recycling endosomes-to-TGN transport involves two SNARE complexes and a Rab6 isoform". J. Cell Biol. 156 (4): 653–64. doi:10.1083/jcb.200110081. PMID 11839770.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Strausberg RL, Feingold EA, Grouse LH; et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMID 12477932.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Zeng Q, Tran TT, Tan HX, Hong W (2003). "The cytoplasmic domain of Vamp4 and Vamp5 is responsible for their correct subcellular targeting: the N-terminal extenSion of VAMP4 contains a dominant autonomous targeting signal for the trans-Golgi network". J. Biol. Chem. 278 (25): 23046–54. doi:10.1074/jbc.M303214200. PMID 12682051.CS1 maint: Multiple names: authors list (link)
• Hinners I, Wendler F, Fei H; et al. (2004). "AP-1 recruitment to VAMP4 is modulated by phosphorylation-dependent binding of PACS-1". EMBO Rep. 4 (12): 1182–9. doi:10.1038/sj.embor.7400018. PMID 14608369.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Ota T, Suzuki Y, Nishikawa T; et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Gerhard DS, Wagner L, Feingold EA; et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMID 15489334.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Rual JF, Venkatesan K, Hao T; et al. (2005). "Towards a proteome-scale map of the human protein-protein interaction network". Nature. 437 (7062): 1173–8. doi:10.1038/nature04209. PMID 16189514.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Olsen JV, Blagoev B, Gnad F; et al. (2006). "Global, in vivo, and site-specific phosphorylation dynamics in signaling networks". Cell. 127 (3): 635–48. doi:10.1016/j.cell.2006.09.026. PMID 17081983.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)