PPP3R1

Protein phosphatase 3 (formerly 2B), regulatory subunit B, alpha isoform
File:PBB Protein PPP3R1 image.jpg PDB rendering based on 1aui.
Available structures PDB Ortholog search: Template:Homologene2PDBe PDBe, Template:Homologene2uniprot RCSB List of PDB id codes 1aui​, 1m63​, 1mf8​, 1tco​, 2p6b​
Identifiers
Symbols	PPP3R1 ; CALNB1; CNB; CNB1
External IDs	Template:OMIM5 Template:MGI HomoloGene: 68099
Gene ontology Molecular function Template:GNF GO Template:GNF GO Template:GNF GO Cellular component Template:GNF GO
Orthologs
Template:GNF Ortholog box
Species	Human	Mouse
Entrez	n/a	n/a
Ensembl	n/a	n/a
UniProt	n/a	n/a
RefSeq (mRNA)	n/a	n/a
RefSeq (protein)	n/a	n/a
Location (UCSC)	n/a	n/a
PubMed search	n/a	n/a

Protein phosphatase 3 (formerly 2B), regulatory subunit B, alpha isoform, also known as PPP3R1, is a human gene.

Further reading

• Guerini D, Krinks MH, Sikela JM; et al. (1990). "Isolation and sequence of a cDNA clone for human calcineurin B, the Ca2+-binding subunit of the Ca2+/calmodulin-stimulated protein phosphatase". DNA. 8 (9): 675–82. PMID 2558868.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Kawamura A, Su MS (1995). "Interaction of FKBP12-FK506 with calcineurin A at the B subunit-binding domain". J. Biol. Chem. 270 (26): 15463–6. PMID 7541044.
• Kissinger CR, Parge HE, Knighton DR; et al. (1996). "Crystal structures of human calcineurin and the human FKBP12-FK506-calcineurin complex". Nature. 378 (6557): 641–4. doi:10.1038/378641a0. PMID 8524402.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Wang MG, Yi H, Guerini D; et al. (1997). "Calcineurin A alpha (PPP3CA), calcineurin A beta (PPP3CB) and calcineurin B (PPP3R1) are located on human chromosomes 4, 10q21-->q22 and 2p16-->p15 respectively". Cytogenet. Cell Genet. 72 (2–3): 236–41. PMID 8978785.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Feng B, Stemmer PM (1999). "Interactions of calcineurin A, calcineurin B, and Ca2+". Biochemistry. 38 (38): 12481–9. PMID 10493818.
• Stratakis CA, Taymans SE (1999). "Structure of the gene coding for calcineurin B (PPP3R1) and mapping to D2S358-D2S1778 (chromosomal region 2p15)". DNA Seq. 9 (4): 227–30. PMID 10520753.
• Nishio H, Matsui K, Tsuji H; et al. (2000). "Immunolocalization of calcineurin and FKBP12, the FK506-binding protein, in Hassall's corpuscles of human thymus and epidermis". Histochem. Cell Biol. 114 (1): 9–14. PMID 10959817.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Sokal I, Li N, Verlinde CL; et al. (2001). "Ca(2+)-binding proteins in the retina: from discovery to etiology of human disease(1)". Biochim. Biophys. Acta. 1498 (2–3): 233–51. PMID 11108966.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Graef IA, Chen F, Chen L; et al. (2001). "Signals transduced by Ca(2+)/calcineurin and NFATc3/c4 pattern the developing vasculature". Cell. 105 (7): 863–75. PMID 11439183.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Al-Daraji WI, Grant KR, Ryan K; et al. (2002). "Localization of calcineurin/NFAT in human skin and psoriasis and inhibition of calcineurin/NFAT activation in human keratinocytes by cyclosporin A.". J. Invest. Dermatol. 118 (5): 779–88. doi:10.1046/j.1523-1747.2002.01709.x. PMID 11982754.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Huai Q, Kim HY, Liu Y; et al. (2002). "Crystal structure of calcineurin-cyclophilin-cyclosporin shows common but distinct recognition of immunophilin-drug complexes". Proc. Natl. Acad. Sci. U.S.A. 99 (19): 12037–42. doi:10.1073/pnas.192206699. PMID 12218175.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Jin L, Harrison SC (2002). "Crystal structure of human calcineurin complexed with cyclosporin A and human cyclophilin". Proc. Natl. Acad. Sci. U.S.A. 99 (21): 13522–6. doi:10.1073/pnas.212504399. PMID 12357034.
• Strausberg RL, Feingold EA, Grouse LH; et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMID 12477932.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Bennasser Y, Badou A, Tkaczuk J, Bahraoui E (2003). "Signaling pathways triggered by HIV-1 Tat in human monocytes to induce TNF-alpha". Virology. 303 (1): 174–80. PMID 12482669.CS1 maint: Multiple names: authors list (link)
• Gerhard DS, Wagner L, Feingold EA; et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMID 15489334.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Bittinger MA, McWhinnie E, Meltzer J; et al. (2005). "Activation of cAMP response element-mediated gene expression by regulated nuclear transport of TORC proteins". Curr. Biol. 14 (23): 2156–61. doi:10.1016/j.cub.2004.11.002. PMID 15589160.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Hillier LW, Graves TA, Fulton RS; et al. (2005). "Generation and annotation of the DNA sequences of human chromosomes 2 and 4". Nature. 434 (7034): 724–31. doi:10.1038/nature03466. PMID 15815621.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Rual JF, Venkatesan K, Hao T; et al. (2005). "Towards a proteome-scale map of the human protein-protein interaction network". Nature. 437 (7062): 1173–8. doi:10.1038/nature04209. PMID 16189514.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Winslow MM, Gallo EM, Neilson JR, Crabtree GR (2006). "The calcineurin phosphatase complex modulates immunogenic B cell responses". Immunity. 24 (2): 141–52. doi:10.1016/j.immuni.2005.12.013. PMID 16473827.CS1 maint: Multiple names: authors list (link)
• Liu Q, Wilkins BJ, Lee YJ; et al. (2006). "Direct interaction and reciprocal regulation between ASK1 and calcineurin-NFAT control cardiomyocyte death and growth". Mol. Cell. Biol. 26 (10): 3785–97. doi:10.1128/MCB.26.10.3785-3797.2006. PMID 16648474.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)