Uridine monophosphate synthetase
Uridine monophosphate synthetase is the enzyme (EC 4.1.1.23) that catalyses the formation of uridine monophosphate (UMP), an energy carrying molecule in many important biosynthetic pathways.
In humans, the gene that codes for this enzyme is located on the long arm of chromosome 3 (3q13).[1]
Deficiency of this enzyme is an inherited autosomal recessive trait in Holstein cattle, and it will cause death before birth.[2]
See also
References
- ↑ Qumsiyeh MB, Valentine MB, Suttle DP. (1989). Localization of the gene for uridine monophosphate synthase to human chromosome region 3q13 by in situ hybridization. Genomics 5(1):160-2.
- ↑ Shanks RD, Robinson JL. (1989). Embryonic mortality attributed to inherited deficiency of uridine monophosphate synthase. J Dairy Sci 72(11):3035-9.
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