SKIL
| SKI-like oncogene | |||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||||
| Symbols | SKIL ; SNO; SnoA; SnoN | ||||||||||
| External IDs | Template:OMIM5 Template:MGI HomoloGene: 3948 | ||||||||||
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| RNA expression pattern | |||||||||||
| File:PBB GE SKIL 206675 s at tn.png | |||||||||||
| More reference expression data | |||||||||||
| Orthologs | |||||||||||
| Template:GNF Ortholog box | |||||||||||
| Species | Human | Mouse | |||||||||
| Entrez | n/a | n/a | |||||||||
| Ensembl | n/a | n/a | |||||||||
| UniProt | n/a | n/a | |||||||||
| RefSeq (mRNA) | n/a | n/a | |||||||||
| RefSeq (protein) | n/a | n/a | |||||||||
| Location (UCSC) | n/a | n/a | |||||||||
| PubMed search | n/a | n/a | |||||||||
SKI-like oncogene, also known as SKIL, is a human gene.[1]
References
Further reading
- Nomura N, Sasamoto S, Ishii S; et al. (1989). "Isolation of human cDNA clones of ski and the ski-related gene, sno". Nucleic Acids Res. 17 (14): 5489–500. PMID 2762147.
- Pearson-White S (1993). "SnoI, a novel alternatively spliced isoform of the ski protooncogene homolog, sno". Nucleic Acids Res. 21 (19): 4632–8. PMID 8233802.
- Pearson-White S, Crittenden R (1997). "Proto-oncogene Sno expression, alternative isoforms and immediate early serum response". Nucleic Acids Res. 25 (14): 2930–7. PMID 9207045.
- Cohen SB, Zheng G, Heyman HC, Stavnezer E (1999). "Heterodimers of the SnoN and Ski oncoproteins form preferentially over homodimers and are more potent transforming agents". Nucleic Acids Res. 27 (4): 1006–14. PMID 9927733.
- Stroschein SL, Wang W, Zhou S; et al. (1999). "Negative feedback regulation of TGF-beta signaling by the SnoN oncoprotein". Science. 286 (5440): 771–4. PMID 10531062.
- Bonni S, Wang HR, Causing CG; et al. (2001). "TGF-beta induces assembly of a Smad2-Smurf2 ubiquitin ligase complex that targets SnoN for degradation". Nat. Cell Biol. 3 (6): 587–95. doi:10.1038/35078562. PMID 11389444.
- Imoto I, Pimkhaokham A, Fukuda Y; et al. (2001). "SNO is a probable target for gene amplification at 3q26 in squamous-cell carcinomas of the esophagus". Biochem. Biophys. Res. Commun. 286 (3): 559–65. doi:10.1006/bbrc.2001.5428. PMID 11511096.
- Stroschein SL, Bonni S, Wrana JL, Luo K (2001). "Smad3 recruits the anaphase-promoting complex for ubiquitination and degradation of SnoN". Genes Dev. 15 (21): 2822–36. doi:10.1101/gad.912901. PMID 11691834.
- Mizuide M, Hara T, Furuya T; et al. (2003). "Two short segments of Smad3 are important for specific interaction of Smad3 with c-Ski and SnoN". J. Biol. Chem. 278 (1): 531–6. doi:10.1074/jbc.C200596200. PMID 12426322.
- Strausberg RL, Feingold EA, Grouse LH; et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMID 12477932.
- Tomsig JL, Snyder SL, Creutz CE (2003). "Identification of targets for calcium signaling through the copine family of proteins. Characterization of a coiled-coil copine-binding motif". J. Biol. Chem. 278 (12): 10048–54. doi:10.1074/jbc.M212632200. PMID 12522145.
- He J, Tegen SB, Krawitz AR; et al. (2003). "The transforming activity of Ski and SnoN is dependent on their ability to repress the activity of Smad proteins". J. Biol. Chem. 278 (33): 30540–7. doi:10.1074/jbc.M304016200. PMID 12764135.
- Colland F, Jacq X, Trouplin V; et al. (2004). "Functional proteomics mapping of a human signaling pathway". Genome Res. 14 (7): 1324–32. doi:10.1101/gr.2334104. PMID 15231748.
- Gerhard DS, Wagner L, Feingold EA; et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMID 15489334.
- Sarker KP, Wilson SM, Bonni S (2005). "SnoN is a cell type-specific mediator of transforming growth factor-beta responses". J. Biol. Chem. 280 (13): 13037–46. doi:10.1074/jbc.M409367200. PMID 15677458.
- Barrios-Rodiles M, Brown KR, Ozdamar B; et al. (2005). "High-throughput mapping of a dynamic signaling network in mammalian cells". Science. 307 (5715): 1621–5. doi:10.1126/science.1105776. PMID 15761153.
- Poser I, Rothhammer T, Dooley S; et al. (2005). "Characterization of Sno expression in malignant melanoma". Int. J. Oncol. 26 (5): 1411–7. PMID 15809735.
- Krakowski AR, Laboureau J, Mauviel A; et al. (2005). "Cytoplasmic SnoN in normal tissues and nonmalignant cells antagonizes TGF-beta signaling by sequestration of the Smad proteins". Proc. Natl. Acad. Sci. U.S.A. 102 (35): 12437–42. doi:10.1073/pnas.0504107102. PMID 16109768.
- Zhu Q, Pearson-White S, Luo K (2006). "Requirement for the SnoN oncoprotein in transforming growth factor beta-induced oncogenic transformation of fibroblast cells". Mol. Cell. Biol. 25 (24): 10731–44. doi:10.1128/MCB.25.24.10731-10744.2005. PMID 16314499.
- Briones-Orta MA, Sosa-Garrocho M, Moreno-Alvarez P; et al. (2006). "SnoN co-repressor binds and represses smad7 gene promoter". Biochem. Biophys. Res. Commun. 341 (3): 889–94. doi:10.1016/j.bbrc.2006.01.041. PMID 16442497.
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