Surfactant protein D

Surfactant, pulmonary-associated protein D
File:PBB Protein SFTPD image.jpg PDB rendering based on 1b08.
Available structures PDB Ortholog search: Template:Homologene2PDBe PDBe, Template:Homologene2uniprot RCSB List of PDB id codes 1b08​, 1m7l​, 1pw9​, 1pwb​, 2ggu​, 2ggx​, 2orj​, 2ork​, 2os9​
Identifiers
Symbols	SFTPD ; COLEC7; PSP-D; SFTP4; SP-D
External IDs	Template:OMIM5 Template:MGI HomoloGene: 2272
Gene ontology Molecular function Template:GNF GO Template:GNF GO Template:GNF GO Cellular component Template:GNF GO Template:GNF GO Template:GNF GO Template:GNF GO Biological process Template:GNF GO Template:GNF GO Template:GNF GO Template:GNF GO Template:GNF GO Template:GNF GO Template:GNF GO Template:GNF GO Template:GNF GO Template:GNF GO Template:GNF GO Template:GNF GO Template:GNF GO Template:GNF GO
RNA expression pattern
File:PBB GE SFTPD 214199 at tn.png
More reference expression data
Orthologs
Template:GNF Ortholog box
Species	Human	Mouse
Entrez	n/a	n/a
Ensembl	n/a	n/a
UniProt	n/a	n/a
RefSeq (mRNA)	n/a	n/a
RefSeq (protein)	n/a	n/a
Location (UCSC)	n/a	n/a
PubMed search	n/a	n/a

Surfactant, pulmonary-associated protein D, also known as SFTPD, is is a collectin.

Further reading

• Hansen S, Holmskov U (1999). "Structural aspects of collectins and receptors for collectins". Immunobiology. 199 (2): 165–89. PMID 9777404.
• Lu J, Willis AC, Reid KB (1992). "Purification, characterization and cDNA cloning of human lung surfactant protein D.". Biochem. J. 284 ( Pt 3): 795–802. PMID 1339284.CS1 maint: Multiple names: authors list (link)
• Ogasawara Y, Kuroki Y, Akino T (1992). "Pulmonary surfactant protein D specifically binds to phosphatidylinositol". J. Biol. Chem. 267 (29): 21244–9. PMID 1400434.CS1 maint: Multiple names: authors list (link)
• Rust K, Grosso L, Zhang V; et al. (1991). "Human surfactant protein D: SP-D contains a C-type lectin carbohydrate recognition domain". Arch. Biochem. Biophys. 290 (1): 116–26. PMID 1898081.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Kuroki Y, Shiratori M, Ogasawara Y; et al. (1991). "Characterization of pulmonary surfactant protein D: its copurification with lipids". Biochim. Biophys. Acta. 1086 (2): 185–90. PMID 1932100.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Crouch E, Persson A, Chang D, Heuser J (1994). "Molecular structure of pulmonary surfactant protein D (SP-D)". J. Biol. Chem. 269 (25): 17311–9. PMID 8006040.CS1 maint: Multiple names: authors list (link)
• Schaeffer E, Guillou F, Part D, Zakin MM (1993). "A different combination of transcription factors modulates the expression of the human transferrin promoter in liver and Sertoli cells". J. Biol. Chem. 268 (31): 23399–408. PMID 8226864.CS1 maint: Multiple names: authors list (link)
• Kölble K, Lu J, Mole SE; et al. (1993). "Assignment of the human pulmonary surfactant protein D gene (SFTP4) to 10q22-q23 close to the surfactant protein A gene cluster". Genomics. 17 (2): 294–8. doi:10.1006/geno.1993.1324. PMID 8406480.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Crouch E, Persson A, Chang D (1993). "Accumulation of surfactant protein D in human pulmonary alveolar proteinosis". Am. J. Pathol. 142 (1): 241–8. PMID 8424457.CS1 maint: Multiple names: authors list (link)
• Crouch E, Rust K, Veile R; et al. (1993). "Genomic organization of human surfactant protein D (SP-D). SP-D is encoded on chromosome 10q22.2-23.1". J. Biol. Chem. 268 (4): 2976–83. PMID 8428971.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Rust K, Bingle L, Mariencheck W; et al. (1996). "Characterization of the human surfactant protein D promoter: transcriptional regulation of SP-D gene expression by glucocorticoids". Am. J. Respir. Cell Mol. Biol. 14 (2): 121–30. PMID 8630261.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Bonaldo MF, Lennon G, Soares MB (1997). "Normalization and subtraction: two approaches to facilitate gene discovery". Genome Res. 6 (9): 791–806. PMID 8889548.CS1 maint: Multiple names: authors list (link)
• Holmskov U, Lawson P, Teisner B; et al. (1997). "Isolation and characterization of a new member of the scavenger receptor superfamily, glycoprotein-340 (gp-340), as a lung surfactant protein-D binding molecule". J. Biol. Chem. 272 (21): 13743–9. PMID 9153228.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Botas C, Poulain F, Akiyama J; et al. (1998). "Altered surfactant homeostasis and alveolar type II cell morphology in mice lacking surfactant protein D.". Proc. Natl. Acad. Sci. U.S.A. 95 (20): 11869–74. PMID 9751757.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Håkansson K, Lim NK, Hoppe HJ, Reid KB (1999). "Crystal structure of the trimeric alpha-helical coiled-coil and the three lectin domains of human lung surfactant protein D.". Structure. 7 (3): 255–64. PMID 10368295.CS1 maint: Multiple names: authors list (link)
• Holmskov U, Mollenhauer J, Madsen J; et al. (1999). "Cloning of gp-340, a putative opsonin receptor for lung surfactant protein D.". Proc. Natl. Acad. Sci. U.S.A. 96 (19): 10794–9. PMID 10485905.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Lausen M, Lynch N, Schlosser A; et al. (1999). "Microfibril-associated protein 4 is present in lung washings and binds to the collagen region of lung surfactant protein D.". J. Biol. Chem. 274 (45): 32234–40. PMID 10542261.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Madsen J, Kliem A, Tornoe I; et al. (2000). "Localization of lung surfactant protein D on mucosal surfaces in human tissues". J. Immunol. 164 (11): 5866–70. PMID 10820266.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Zhang L, Ikegami M, Crouch EC; et al. (2001). "Activity of pulmonary surfactant protein-D (SP-D) in vivo is dependent on oligomeric structure". J. Biol. Chem. 276 (22): 19214–9. doi:10.1074/jbc.M010191200. PMID 11278637.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)

See also

• pulmonary surfactant

External links

• Surfactant+Protein+D at the US National Library of Medicine Medical Subject Headings (MeSH)