SORBS1

Sorbin and SH3 domain containing 1
File:PBB Protein SORBS1 image.jpg PDB rendering based on 2dl3.
Available structures PDB Ortholog search: Template:Homologene2PDBe PDBe, Template:Homologene2uniprot RCSB List of PDB id codes 2dl3​
Identifiers
Symbols	SORBS1 ; CAP; DKFZp451C066; DKFZp586P1422; FLAF2; FLJ12406; KIAA1296; R85FL; SH3D5; SH3P12; SORB1
External IDs	Template:OMIM5 Template:MGI HomoloGene: 83252
Gene ontology Molecular function Template:GNF GO Template:GNF GO Template:GNF GO Cellular component Template:GNF GO Template:GNF GO Template:GNF GO Template:GNF GO Template:GNF GO Template:GNF GO Biological process Template:GNF GO Template:GNF GO Template:GNF GO Template:GNF GO Template:GNF GO
RNA expression pattern
File:PBB GE SORBS1 211819 s at tn.png
File:PBB GE SORBS1 218087 s at tn.png
File:PBB GE SORBS1 211705 s at tn.png
More reference expression data
Orthologs
Template:GNF Ortholog box
Species	Human	Mouse
Entrez	n/a	n/a
Ensembl	n/a	n/a
UniProt	n/a	n/a
RefSeq (mRNA)	n/a	n/a
RefSeq (protein)	n/a	n/a
Location (UCSC)	n/a	n/a
PubMed search	n/a	n/a

Sorbin and SH3 domain containing 1, also known as SORBS1, is a human gene.

Further reading

• Kioka N (2003). "[A novel adaptor protein family regulating cytoskeletal organization and signal transduction--Vinexin, CAP/ponsin, ArgBP2]". Seikagaku. 74 (11): 1356–60. PMID 12510380.
• Ribon V, Herrera R, Kay BK, Saltiel AR (1998). "A role for CAP, a novel, multifunctional Src homology 3 domain-containing protein in formation of actin stress fibers and focal adhesions". J. Biol. Chem. 273 (7): 4073–80. PMID 9461600.CS1 maint: Multiple names: authors list (link)
• Mandai K, Nakanishi H, Satoh A; et al. (1999). "Ponsin/SH3P12: an l-afadin- and vinculin-binding protein localized at cell-cell and cell-matrix adherens junctions". J. Cell Biol. 144 (5): 1001–17. PMID 10085297.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Asakura T, Nakanishi H, Sakisaka T; et al. (2000). "Similar and differential behaviour between the nectin-afadin-ponsin and cadherin-catenin systems during the formation and disruption of the polarized junctional alignment in epithelial cells". Genes Cells. 4 (10): 573–81. PMID 10583506.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Nagase T, Kikuno R, Ishikawa KI; et al. (2000). "Prediction of the coding sequences of unidentified human genes. XVI. The complete sequences of 150 new cDNA clones from brain which code for large proteins in vitro". DNA Res. 7 (1): 65–73. PMID 10718198.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Baumann CA, Ribon V, Kanzaki M; et al. (2000). "CAP defines a second signalling pathway required for insulin-stimulated glucose transport". Nature. 407 (6801): 202–7. doi:10.1038/35025089. PMID 11001060.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Hartley JL, Temple GF, Brasch MA (2001). "DNA cloning using in vitro site-specific recombination". Genome Res. 10 (11): 1788–95. PMID 11076863.CS1 maint: Multiple names: authors list (link)
• Wiemann S, Weil B, Wellenreuther R; et al. (2001). "Toward a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs". Genome Res. 11 (3): 422–35. doi:10.1101/gr.154701. PMID 11230166.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Lebre AS, Jamot L, Takahashi J; et al. (2001). "Ataxin-7 interacts with a Cbl-associated protein that it recruits into neuronal intranuclear inclusions". Hum. Mol. Genet. 10 (11): 1201–13. PMID 11371513.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Lin WH, Huang CJ, Liu MW; et al. (2001). "Cloning, mapping, and characterization of the human sorbin and SH3 domain containing 1 (SORBS1) gene: a protein associated with c-Abl during insulin signaling in the hepatoma cell line Hep3B". Genomics. 74 (1): 12–20. doi:10.1006/geno.2001.6541. PMID 11374898.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Kimura A, Baumann CA, Chiang SH, Saltiel AR (2001). "The sorbin homology domain: a motif for the targeting of proteins to lipid rafts". Proc. Natl. Acad. Sci. U.S.A. 98 (16): 9098–103. doi:10.1073/pnas.151252898. PMID 11481476.CS1 maint: Multiple names: authors list (link)
• Lin WH, Chiu KC, Chang HM; et al. (2002). "Molecular scanning of the human sorbin and SH3-domain-containing-1 (SORBS1) gene: positive association of the T228A polymorphism with obesity and type 2 diabetes". Hum. Mol. Genet. 10 (17): 1753–60. PMID 11532984.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Cowan CA, Henkemeyer M (2001). "The SH2/SH3 adaptor Grb4 transduces B-ephrin reverse signals". Nature. 413 (6852): 174–9. doi:10.1038/35093123. PMID 11557983.
• Liu J, Kimura A, Baumann CA, Saltiel AR (2002). "APS facilitates c-Cbl tyrosine phosphorylation and GLUT4 translocation in response to insulin in 3T3-L1 adipocytes". Mol. Cell. Biol. 22 (11): 3599–609. PMID 11997497.CS1 maint: Multiple names: authors list (link)
• Xie J, Cai T, Zhang H; et al. (2003). "The zinc-finger transcription factor INSM1 is expressed during embryo development and interacts with the Cbl-associated protein". Genomics. 80 (1): 54–61. PMID 12079283.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Nakayama M, Kikuno R, Ohara O (2003). "Protein-protein interactions between large proteins: two-hybrid screening using a functionally classified library composed of long cDNAs". Genome Res. 12 (11): 1773–84. doi:10.1101/gr.406902. PMID 12421765.CS1 maint: Multiple names: authors list (link)
• Strausberg RL, Feingold EA, Grouse LH; et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMID 12477932.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Vandenbroere I, Paternotte N, Dumont JE; et al. (2003). "The c-Cbl-associated protein and c-Cbl are two new partners of the SH2-containing inositol polyphosphate 5-phosphatase SHIP2". Biochem. Biophys. Res. Commun. 300 (2): 494–500. PMID 12504111.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Yang WS, Lee WJ, Huang KC; et al. (2003). "mRNA levels of the insulin-signaling molecule SORBS1 in the adipose depots of nondiabetic women". Obes. Res. 11 (4): 586–90. PMID 12690089.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)