BICD1

Bicaudal D homolog 1 (Drosophila)
Identifiers
Symbols	BICD1 ; BICD
External IDs	Template:OMIM5 Template:MGI HomoloGene: 37518
Gene ontology Molecular function Template:GNF GO Cellular component Template:GNF GO Biological process Template:GNF GO Template:GNF GO Template:GNF GO
RNA expression pattern
More reference expression data
Orthologs
Template:GNF Ortholog box
Species	Human	Mouse
Entrez	n/a	n/a
Ensembl	n/a	n/a
UniProt	n/a	n/a
RefSeq (mRNA)	n/a	n/a
RefSeq (protein)	n/a	n/a
Location (UCSC)	n/a	n/a
PubMed search	n/a	n/a

Bicaudal D homolog 1 (Drosophila), also known as BICD1, is a human gene.

This gene is one of two human homologs of Drosophila bicaudal-D. It has been implicated in COPI-independent membrane transport from the Golgi apparatus to the endoplasmic reticulum. Two alternative splice variants have been described. Other alternative splice variants that encode different protein isoforms have been described but their full-length nature has not been determined.

Further reading

• Barr FA, Short B (2004). "Golgins in the structure and dynamics of the Golgi apparatus". Curr. Opin. Cell Biol. 15 (4): 405–13. PMID 12892780.
• Claussen M, Suter B (2006). "BicD-dependent localization processes: from Drosophilia development to human cell biology". Ann. Anat. 187 (5–6): 539–53. PMID 16320833.
• Baens M, Aerssens J, van Zand K; et al. (1996). "Isolation and regional assignment of human chromosome 12p cDNAs". Genomics. 29 (1): 44–52. doi:10.1006/geno.1995.1213. PMID 8530100.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Baens M, Marynen P (1998). "A human homologue (BICD1) of the Drosophila bicaudal-D gene". Genomics. 45 (3): 601–6. doi:10.1006/geno.1997.4971. PMID 9367685.
• Short B, Preisinger C, Schaletzky J; et al. (2003). "The Rab6 GTPase regulates recruitment of the dynactin complex to Golgi membranes". Curr. Biol. 12 (20): 1792–5. PMID 12401177.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Matanis T, Akhmanova A, Wulf P; et al. (2003). "Bicaudal-D regulates COPI-independent Golgi-ER transport by recruiting the dynein-dynactin motor complex". Nat. Cell Biol. 4 (12): 986–92. doi:10.1038/ncb891. PMID 12447383.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Strausberg RL, Feingold EA, Grouse LH; et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMID 12477932.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Tomsig JL, Snyder SL, Creutz CE (2003). "Identification of targets for calcium signaling through the copine family of proteins. Characterization of a coiled-coil copine-binding motif". J. Biol. Chem. 278 (12): 10048–54. doi:10.1074/jbc.M212632200. PMID 12522145.CS1 maint: Multiple names: authors list (link)
• Ota T, Suzuki Y, Nishikawa T; et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Gerhard DS, Wagner L, Feingold EA; et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMID 15489334.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Kimura K, Wakamatsu A, Suzuki Y; et al. (2006). "Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes". Genome Res. 16 (1): 55–65. doi:10.1101/gr.4039406. PMID 16344560.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Fuchs E, Short B, Barr FA (2006). "Assay and properties of rab6 interaction with dynein-dynactin complexes". Meth. Enzymol. 403: 607–18. doi:10.1016/S0076-6879(05)03053-3. PMID 16473624.CS1 maint: Multiple names: authors list (link)
• Moorhead AR, Rzomp KA, Scidmore MA (2007). "The Rab6 effector Bicaudal D1 associates with Chlamydia trachomatis inclusions in a biovar-specific manner". Infect. Immun. 75 (2): 781–91. doi:10.1128/IAI.01447-06. PMID 17101644.CS1 maint: Multiple names: authors list (link)
• Fumoto K, Hoogenraad CC, Kikuchi A (2007). "GSK-3beta-regulated interaction of BICD with dynein is involved in microtubule anchorage at centrosome". EMBO J. 25 (24): 5670–82. doi:10.1038/sj.emboj.7601459. PMID 17139249.CS1 maint: Multiple names: authors list (link)
• Wanschers BF, van de Vorstenbosch R, Schlager MA; et al. (2007). "A role for the Rab6B Bicaudal-D1 interaction in retrograde transport in neuronal cells". Exp. Cell Res. 313 (16): 3408–20. doi:10.1016/j.yexcr.2007.05.032. PMID 17707369.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)