GJA3

Gap junction protein, alpha 3, 46kDa
Identifiers
Symbols	GJA3 ; CX46; CZP3
External IDs	Template:OMIM5 Template:MGI HomoloGene: 9670
Gene ontology Molecular function Template:GNF GO Cellular component Template:GNF GO Template:GNF GO Template:GNF GO Biological process Template:GNF GO Template:GNF GO Template:GNF GO
RNA expression pattern
More reference expression data
Orthologs
Template:GNF Ortholog box
Species	Human	Mouse
Entrez	n/a	n/a
Ensembl	n/a	n/a
UniProt	n/a	n/a
RefSeq (mRNA)	n/a	n/a
RefSeq (protein)	n/a	n/a
Location (UCSC)	n/a	n/a
PubMed search	n/a	n/a

Gap junction protein, alpha 3, 46kDa, also known as GJA3, is a human gene.

Further reading

• Hsieh CL, Kumar NM, Gilula NB, Francke U (1991). "Distribution of genes for gap junction membrane channel proteins on human and mouse chromosomes". Somat. Cell Mol. Genet. 17 (2): 191–200. PMID 1849321.CS1 maint: Multiple names: authors list (link)
• Willecke K, Jungbluth S, Dahl E; et al. (1991). "Six genes of the human connexin gene family coding for gap junctional proteins are assigned to four different human chromosomes". Eur. J. Cell Biol. 53 (2): 275–80. PMID 1964417.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Rosenberg AM, Gole GA (1982). "Morning Glory Syndrome: a report of two cases". Australian journal of ophthalmology. 9 (4): 263–5. PMID 7342922.
• Mackay D, Ionides A, Berry V; et al. (1997). "A new locus for dominant "zonular pulverulent" cataract, on chromosome 13". Am. J. Hum. Genet. 60 (6): 1474–8. PMID 9199569.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Gong X, Li E, Klier G; et al. (1998). "Disruption of alpha3 connexin gene leads to proteolysis and cataractogenesis in mice". Cell. 91 (6): 833–43. PMID 9413992.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Dunia I, Recouvreur M, Nicolas P; et al. (1998). "Assembly of connexins and MP26 in lens fiber plasma membranes studied by SDS-fracture immunolabeling". J. Cell. Sci. 111 ( Pt 15): 2109–20. PMID 9664032.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Mackay D, Ionides A, Kibar Z; et al. (1999). "Connexin46 mutations in autosomal dominant congenital cataract". Am. J. Hum. Genet. 64 (5): 1357–64. PMID 10205266.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Rees MI, Watts P, Fenton I; et al. (2000). "Further evidence of autosomal dominant congenital zonular pulverulent cataracts linked to 13q11 (CZP3) and a novel mutation in connexin 46 (GJA3)". Hum. Genet. 106 (2): 206–9. PMID 10746562.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Das Sarma J, Meyer RA, Wang F; et al. (2002). "Multimeric connexin interactions prior to the trans-Golgi network". J. Cell. Sci. 114 (Pt 22): 4013–24. PMID 11739633.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Schubert AL, Schubert W, Spray DC, Lisanti MP (2002). "Connexin family members target to lipid raft domains and interact with caveolin-1". Biochemistry. 41 (18): 5754–64. PMID 11980479.CS1 maint: Multiple names: authors list (link)
• Strausberg RL, Feingold EA, Grouse LH; et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMID 12477932.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Nielsen PA, Baruch A, Shestopalov VI; et al. (2004). "Lens connexins alpha3Cx46 and alpha8Cx50 interact with zonula occludens protein-1 (ZO-1)". Mol. Biol. Cell. 14 (6): 2470–81. doi:10.1091/mbc.E02-10-0637. PMID 12808044.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Jiang H, Jin Y, Bu L; et al. (2003). "A novel mutation in GJA3 (connexin46) for autosomal dominant congenital nuclear pulverulent cataract". Mol. Vis. 9: 579–83. PMID 14627959.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Dunham A, Matthews LH, Burton J; et al. (2004). "The DNA sequence and analysis of human chromosome 13". Nature. 428 (6982): 522–8. doi:10.1038/nature02379. PMID 15057823.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Bennett TM, Mackay DS, Knopf HL, Shiels A (2004). "A novel missense mutation in the gene for gap-junction protein alpha3 (GJA3) associated with autosomal dominant "nuclear punctate" cataracts linked to chromosome 13q". Mol. Vis. 10: 376–82. PMID 15208569.CS1 maint: Multiple names: authors list (link)
• Burdon KP, Wirth MG, Mackey DA; et al. (2004). "A novel mutation in the Connexin 46 gene causes autosomal dominant congenital cataract with incomplete penetrance". J. Med. Genet. 41 (8): e106. doi:10.1136/jmg.2004.018333. PMID 15286166.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Lin D, Lobell S, Jewell A, Takemoto DJ (2004). "Differential phosphorylation of connexin46 and connexin50 by H2O2 activation of protein kinase Cgamma". Mol. Vis. 10: 688–95. PMID 15467523.CS1 maint: Multiple names: authors list (link)
• Gerhard DS, Wagner L, Feingold EA; et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMID 15489334.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Devi RR, Reena C, Vijayalakshmi P (2006). "Novel mutations in GJA3 associated with autosomal dominant congenital cataract in the Indian population". Mol. Vis. 11: 846–52. PMID 16254549.CS1 maint: Multiple names: authors list (link)
• Addison PK, Berry V, Holden KR; et al. (2006). "A novel mutation in the connexin 46 gene (GJA3) causes autosomal dominant zonular pulverulent cataract in a Hispanic family". Mol. Vis. 12: 791–5. PMID 16885921.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)