TFDP1

Transcription factor Dp-1
File:PBB Protein TFDP1 image.jpg PDB rendering based on 2aze.
Available structures PDB Ortholog search: Template:Homologene2PDBe PDBe, Template:Homologene2uniprot RCSB List of PDB id codes 2aze​
Identifiers
Symbols	TFDP1 ; DP1; DRTF1; Dp-1
External IDs	Template:OMIM5 Template:MGI HomoloGene: 38276
Gene ontology Molecular function Template:GNF GO Template:GNF GO Cellular component Template:GNF GO Template:GNF GO Biological process Template:GNF GO Template:GNF GO Template:GNF GO Template:GNF GO Template:GNF GO Template:GNF GO
Orthologs
Template:GNF Ortholog box
Species	Human	Mouse
Entrez	n/a	n/a
Ensembl	n/a	n/a
UniProt	n/a	n/a
RefSeq (mRNA)	n/a	n/a
RefSeq (protein)	n/a	n/a
Location (UCSC)	n/a	n/a
PubMed search	n/a	n/a

Transcription factor Dp-1, also known as TFDP1, is a human gene.

The E2F transcription factor family (see MIM 189971) regulates the expression of various cellular promoters, particularly those involved in the cell cycle. E2F factors bind to DNA as homodimers or heterodimers in association with dimerization partner DP1. TFDP1 may be the first example of a family of related transcription factors; see TFDP2 (MIM 602160).[supplied by OMIM]

Further reading

• Wu CL, Zukerberg LR, Ngwu C; et al. (1995). "In vivo association of E2F and DP family proteins". Mol. Cell. Biol. 15 (5): 2536–46. PMID 7739537.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Hijmans EM, Voorhoeve PM, Beijersbergen RL; et al. (1995). "E2F-5, a new E2F family member that interacts with p130 in vivo". Mol. Cell. Biol. 15 (6): 3082–9. PMID 7760804.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Sardet C, Vidal M, Cobrinik D; et al. (1995). "E2F-4 and E2F-5, two members of the E2F family, are expressed in the early phases of the cell cycle". Proc. Natl. Acad. Sci. U.S.A. 92 (6): 2403–7. PMID 7892279.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Ginsberg D, Vairo G, Chittenden T; et al. (1994). "E2F-4, a new member of the E2F transcription factor family, interacts with p107". Genes Dev. 8 (22): 2665–79. PMID 7958924.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Beijersbergen RL, Kerkhoven RM, Zhu L; et al. (1994). "E2F-4, a new member of the E2F gene family, has oncogenic activity and associates with p107 in vivo". Genes Dev. 8 (22): 2680–90. PMID 7958925.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Bandara LR, Lam EW, Sørensen TS; et al. (1994). "DP-1: a cell cycle-regulated and phosphorylated component of transcription factor DRTF1/E2F which is functionally important for recognition by pRb and the adenovirus E4 orf 6/7 protein". EMBO J. 13 (13): 3104–14. PMID 8039504.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Helin K, Wu CL, Fattaey AR; et al. (1993). "Heterodimerization of the transcription factors E2F-1 and DP-1 leads to cooperative trans-activation". Genes Dev. 7 (10): 1850–61. PMID 8405995.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Girling R, Partridge JF, Bandara LR; et al. (1993). "A new component of the transcription factor DRTF1/E2F". Nature. 365 (6445): 468. doi:10.1038/365468d0. PMID 8413592.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Rogers KT, Higgins PD, Milla MM; et al. (1996). "DP-2, a heterodimeric partner of E2F: identification and characterization of DP-2 proteins expressed in vivo". Proc. Natl. Acad. Sci. U.S.A. 93 (15): 7594–9. PMID 8755520.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Sørensen TS, Girling R, Lee CW; et al. (1996). "Functional interaction between DP-1 and p53". Mol. Cell. Biol. 16 (10): 5888–95. PMID 8816502.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Vidal M, Braun P, Chen E; et al. (1996). "Genetic characterization of a mammalian protein-protein interaction domain by using a yeast reverse two-hybrid system". Proc. Natl. Acad. Sci. U.S.A. 93 (19): 10321–6. PMID 8816798.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Magae J, Wu CL, Illenye S; et al. (1997). "Nuclear localization of DP and E2F transcription factors by heterodimeric partners and retinoblastoma protein family members". J. Cell. Sci. 109 ( Pt 7): 1717–26. PMID 8832394.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Hofmann F, Livingston DM (1996). "Differential effects of cdk2 and cdk3 on the control of pRb and E2F function during G1 exit". Genes Dev. 10 (7): 851–61. PMID 8846921.
• Zhang Y, Venkatraj VS, Fischer SG; et al. (1997). "Genomic cloning and chromosomal assignment of the E2F dimerization partner TFDP gene family". Genomics. 39 (1): 95–8. doi:10.1006/geno.1996.4473. PMID 9027491.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Trimarchi JM, Fairchild B, Verona R; et al. (1998). "E2F-6, a member of the E2F family that can behave as a transcriptional repressor". Proc. Natl. Acad. Sci. U.S.A. 95 (6): 2850–5. PMID 9501179.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Cartwright P, Müller H, Wagener C; et al. (1998). "E2F-6: a novel member of the E2F family is an inhibitor of E2F-dependent transcription". Oncogene. 17 (5): 611–23. doi:10.1038/sj.onc.1201975. PMID 9704927.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Timchenko NA, Wilde M, Darlington GJ (1999). "C/EBPalpha regulates formation of S-phase-specific E2F-p107 complexes in livers of newborn mice". Mol. Cell. Biol. 19 (4): 2936–45. PMID 10082561.CS1 maint: Multiple names: authors list (link)
• Lam EW, Glassford J, van der Sman J; et al. (1999). "Modulation of E2F activity in primary mouse B cells following stimulation via surface IgM and CD40 receptors". Eur. J. Immunol. 29 (10): 3380–9. PMID 10540350.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Sansal I, Dupont E, Toru D; et al. (2000). "NPDC-1, a regulator of neural cell proliferation and differentiation, interacts with E2F-1, reduces its binding to DNA and modulates its transcriptional activity". Oncogene. 19 (43): 5000–9. doi:10.1038/sj.onc.1203843. PMID 11042687.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Hsu SI, Yang CM, Sim KG; et al. (2001). "TRIP-Br: a novel family of PHD zinc finger- and bromodomain-interacting proteins that regulate the transcriptional activity of E2F-1/DP-1". EMBO J. 20 (9): 2273–85. doi:10.1093/emboj/20.9.2273. PMID 11331592.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)