SH3GL3

SH3-domain GRB2-like 3
File:PBB Protein SH3GL3 image.jpg PDB rendering based on 2ew3.
Available structures PDB Ortholog search: Template:Homologene2PDBe PDBe, Template:Homologene2uniprot RCSB List of PDB id codes 2ew3​
Identifiers
Symbols	SH3GL3 ; CNSA3; EEN-2B-L3; EEN-B2; HsT19371; SH3D2C; SH3P13
External IDs	Template:OMIM5 Template:MGI HomoloGene: 37723
Gene ontology Molecular function Template:GNF GO Template:GNF GO Cellular component Template:GNF GO Biological process Template:GNF GO Template:GNF GO
RNA expression pattern
File:PBB GE SH3GL3 205637 s at tn.png
File:PBB GE SH3GL3 gnf1h02191 at tn.png
File:PBB GE SH3GL3 gnf1h02192 x at tn.png
More reference expression data
Orthologs
Template:GNF Ortholog box
Species	Human	Mouse
Entrez	n/a	n/a
Ensembl	n/a	n/a
UniProt	n/a	n/a
RefSeq (mRNA)	n/a	n/a
RefSeq (protein)	n/a	n/a
Location (UCSC)	n/a	n/a
PubMed search	n/a	n/a

SH3-domain GRB2-like 3, also known as SH3GL3, is a human gene.

Further reading

• So CW, Caldas C, Liu MM; et al. (1997). "EEN encodes for a member of a new family of proteins containing an Src homology 3 domain and is the third gene located on chromosome 19p13 that fuses to MLL in human leukemia". Proc. Natl. Acad. Sci. U.S.A. 94 (6): 2563–8. PMID 9122235.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Giachino C, Lantelme E, Lanzetti L; et al. (1997). "A novel SH3-containing human gene family preferentially expressed in the central nervous system". Genomics. 41 (3): 427–34. PMID 9169142.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Ringstad N, Nemoto Y, De Camilli P (1997). "The SH3p4/Sh3p8/SH3p13 protein family: binding partners for synaptojanin and dynamin via a Grb2-like Src homology 3 domain". Proc. Natl. Acad. Sci. U.S.A. 94 (16): 8569–74. PMID 9238017.CS1 maint: Multiple names: authors list (link)
• Sittler A, Wälter S, Wedemeyer N; et al. (1998). "SH3GL3 associates with the Huntingtin exon 1 protein and promotes the formation of polygln-containing protein aggregates". Mol. Cell. 2 (4): 427–36. PMID 9809064.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Tang Y, Hu LA, Miller WE; et al. (1999). "Identification of the endophilins (SH3p4/p8/p13) as novel binding partners for the beta1-adrenergic receptor". Proc. Natl. Acad. Sci. U.S.A. 96 (22): 12559–64. PMID 10535961.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Cestra G, Castagnoli L, Dente L; et al. (1999). "The SH3 domains of endophilin and amphiphysin bind to the proline-rich region of synaptojanin 1 at distinct sites that display an unconventional binding specificity". J. Biol. Chem. 274 (45): 32001–7. PMID 10542231.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• So CW, So CK, Cheung N; et al. (2000). "The interaction between EEN and Abi-1, two MLL fusion partners, and synaptojanin and dynamin: implications for leukaemogenesis". Leukemia. 14 (4): 594–601. PMID 10764144.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• So CW, Sham MH, Chew SL; et al. (2000). "Expression and protein-binding studies of the EEN gene family, new interacting partners for dynamin, synaptojanin and huntingtin proteins". Biochem. J. 348 Pt 2: 447–58. PMID 10816441.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Petrelli A, Gilestro GF, Lanzardo S; et al. (2002). "The endophilin-CIN85-Cbl complex mediates ligand-dependent downregulation of c-Met". Nature. 416 (6877): 187–90. doi:10.1038/416187a. PMID 11894096.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Chatellard-Causse C, Blot B, Cristina N; et al. (2002). "Alix (ALG-2-interacting protein X), a protein involved in apoptosis, binds to endophilins and induces cytoplasmic vacuolization". J. Biol. Chem. 277 (32): 29108–15. doi:10.1074/jbc.M204019200. PMID 12034747.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Verdier F, Valovka T, Zhyvoloup A; et al. (2002). "Ruk is ubiquitinated but not degraded by the proteasome". Eur. J. Biochem. 269 (14): 3402–8. PMID 12135478.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Szymkiewicz I, Kowanetz K, Soubeyran P; et al. (2002). "CIN85 participates in Cbl-b-mediated down-regulation of receptor tyrosine kinases". J. Biol. Chem. 277 (42): 39666–72. doi:10.1074/jbc.M205535200. PMID 12177062.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Otsuki M, Itoh T, Takenawa T (2003). "Neural Wiskott-Aldrich syndrome protein is recruited to rafts and associates with endophilin A in response to epidermal growth factor". J. Biol. Chem. 278 (8): 6461–9. doi:10.1074/jbc.M207433200. PMID 12477732.CS1 maint: Multiple names: authors list (link)
• Strausberg RL, Feingold EA, Grouse LH; et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMID 12477932.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Yam JW, Jin DY, So CW, Chan LC (2004). "Identification and characterization of EBP, a novel EEN binding protein that inhibits Ras signaling and is recruited into the nucleus by the MLL-EEN fusion protein". Blood. 103 (4): 1445–53. doi:10.1182/blood-2003-07-2452. PMID 14551139.CS1 maint: Multiple names: authors list (link)
• Goehler H, Lalowski M, Stelzl U; et al. (2004). "A protein interaction network links GIT1, an enhancer of huntingtin aggregation, to Huntington's disease". Mol. Cell. 15 (6): 853–65. doi:10.1016/j.molcel.2004.09.016. PMID 15383276.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Trevaskis J, Walder K, Foletta V; et al. (2005). "Src homology 3-domain growth factor receptor-bound 2-like (endophilin) interacting protein 1, a novel neuronal protein that regulates energy balance". Endocrinology. 146 (9): 3757–64. doi:10.1210/en.2005-0282. PMID 15919751.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Ralser M, Nonhoff U, Albrecht M; et al. (2005). "Ataxin-2 and huntingtin interact with endophilin-A complexes to function in plastin-associated pathways". Hum. Mol. Genet. 14 (19): 2893–909. doi:10.1093/hmg/ddi321. PMID 16115810.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Stelzl U, Worm U, Lalowski M; et al. (2005). "A human protein-protein interaction network: a resource for annotating the proteome". Cell. 122 (6): 957–68. doi:10.1016/j.cell.2005.08.029. PMID 16169070.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Lim J, Hao T, Shaw C; et al. (2006). "A protein-protein interaction network for human inherited ataxias and disorders of Purkinje cell degeneration". Cell. 125 (4): 801–14. doi:10.1016/j.cell.2006.03.032. PMID 16713569.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)