CHST6

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Carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 6
Identifiers
Symbols CHST6 ; MCDC1
External IDs Template:OMIM5 Template:MGI HomoloGene56927
Orthologs
Template:GNF Ortholog box
Species Human Mouse
Entrez n/a n/a
Ensembl n/a n/a
UniProt n/a n/a
RefSeq (mRNA) n/a n/a
RefSeq (protein) n/a n/a
Location (UCSC) n/a n/a
PubMed search n/a n/a

Carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 6, also known as CHST6, is a human gene.[1]


References

  1. "Entrez Gene: CHST6 carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 6".

Further reading

  • Bernstein HB, Compans RW (1992). "Sulfation of the human immunodeficiency virus envelope glycoprotein". J. Virol. 66 (12): 6953–9. PMID 1433500.
  • Shilatifard A, Merkle RK, Helland DE; et al. (1993). "Complex-type N-linked oligosaccharides of gp120 from human immunodeficiency virus type 1 contain sulfated N-acetylglucosamine". J. Virol. 67 (2): 943–52. PMID 8419650.
  • Vance JM, Jonasson F, Lennon F; et al. (1996). "Linkage of a gene for macular corneal dystrophy to chromosome 16". Am. J. Hum. Genet. 58 (4): 757–62. PMID 8644739.
  • Uchimura K, Fasakhany F, Kadomatsu K; et al. (2000). "Diversity of N-acetylglucosamine-6-O-sulfotransferases: molecular cloning of a novel enzyme with different distribution and specificities". Biochem. Biophys. Res. Commun. 274 (2): 291–6. doi:10.1006/bbrc.2000.3141. PMID 10913333.
  • Akama TO, Nishida K, Nakayama J; et al. (2000). "Macular corneal dystrophy type I and type II are caused by distinct mutations in a new sulphotransferase gene". Nat. Genet. 26 (2): 237–41. doi:10.1038/79987. PMID 11017086.
  • Spiro MJ, Spiro RG (2001). "Sulfation of the N-linked oligosaccharides of influenza virus hemagglutinin: temporal relationships and localization of sulfotransferases". Glycobiology. 10 (11): 1235–42. PMID 11087716.
  • Liu NP, Dew-Knight S, Rayner M; et al. (2001). "Mutations in corneal carbohydrate sulfotransferase 6 gene (CHST6) cause macular corneal dystrophy in Iceland". Mol. Vis. 6: 261–4. PMID 11139648.
  • Hemmerich S, Lee JK, Bhakta S; et al. (2001). "Chromosomal localization and genomic organization for the galactose/ N-acetylgalactosamine/N-acetylglucosamine 6-O-sulfotransferase gene family". Glycobiology. 11 (1): 75–87. PMID 11181564.
  • Akama TO, Nakayama J, Nishida K; et al. (2001). "Human corneal GlcNac 6-O-sulfotransferase and mouse intestinal GlcNac 6-O-sulfotransferase both produce keratan sulfate". J. Biol. Chem. 276 (19): 16271–8. doi:10.1074/jbc.M009995200. PMID 11278593.
  • Bartes A, Bhakta S, Hemmerich S (2001). "Sulfation of endothelial mucin by corneal keratan N-acetylglucosamine 6-O-sulfotransferase (GST-4beta)". Biochem. Biophys. Res. Commun. 282 (4): 928–33. doi:10.1006/bbrc.2001.4668. PMID 11352640.
  • El-Ashry MF, Abd El-Aziz MM, Wilkins S; et al. (2002). "Identification of novel mutations in the carbohydrate sulfotransferase gene (CHST6) causing macular corneal dystrophy". Invest. Ophthalmol. Vis. Sci. 43 (2): 377–82. PMID 11818380.
  • Akama TO, Misra AK, Hindsgaul O, Fukuda MN (2003). "Enzymatic synthesis in vitro of the disulfated disaccharide unit of corneal keratan sulfate". J. Biol. Chem. 277 (45): 42505–13. doi:10.1074/jbc.M207412200. PMID 12218059.
  • Strausberg RL, Feingold EA, Grouse LH; et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMID 12477932.
  • Niel F, Ellies P, Dighiero P; et al. (2003). "Truncating mutations in the carbohydrate sulfotransferase 6 gene (CHST6) result in macular corneal dystrophy". Invest. Ophthalmol. Vis. Sci. 44 (7): 2949–53. PMID 12824236.
  • Iida-Hasegawa N, Furuhata A, Hayatsu H; et al. (2003). "Mutations in the CHST6 gene in patients with macular corneal dystrophy: immunohistochemical evidence of heterogeneity". Invest. Ophthalmol. Vis. Sci. 44 (8): 3272–7. PMID 12882769.
  • Ha NT, Chau HM, Cung le X; et al. (2003). "Mutation analysis of the carbohydrate sulfotransferase gene in Vietnamese with macular corneal dystrophy". Invest. Ophthalmol. Vis. Sci. 44 (8): 3310–6. PMID 12882775.
  • Ha NT, Chau HM, Cung le X; et al. (2003). "Identification of novel mutations of the CHST6 gene in Vietnamese families affected with macular corneal dystrophy in two generations". Cornea. 22 (6): 508–11. PMID 12883341.
  • Warren JF, Aldave AJ, Srinivasan M; et al. (2003). "Novel mutations in the CHST6 gene associated with macular corneal dystrophy in southern India". Arch. Ophthalmol. 121 (11): 1608–12. doi:10.1001/archopht.121.11.1608. PMID 14609920.
  • Sultana A, Sridhar MS, Jagannathan A; et al. (2004). "Novel mutations of the carbohydrate sulfotransferase-6 (CHST6) gene causing macular corneal dystrophy in India". Mol. Vis. 9: 730–4. PMID 14735064.
  • Abbruzzese C, Kuhn U, Molina F; et al. (2004). "Novel mutations in the CHST6 gene causing macular corneal dystrophy". Clin. Genet. 65 (2): 120–5. PMID 14984470.

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