HSD17B2

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Hydroxysteroid (17-beta) dehydrogenase 2
Identifiers
Symbols HSD17B2 ; EDH17B2; HSD17
External IDs Template:OMIM5 Template:MGI HomoloGene31076
RNA expression pattern
More reference expression data
Orthologs
Template:GNF Ortholog box
Species Human Mouse
Entrez n/a n/a
Ensembl n/a n/a
UniProt n/a n/a
RefSeq (mRNA) n/a n/a
RefSeq (protein) n/a n/a
Location (UCSC) n/a n/a
PubMed search n/a n/a

Hydroxysteroid (17-beta) dehydrogenase 2, also known as HSD17B2, is a human gene.[1]


References

  1. "Entrez Gene: HSD17B2 hydroxysteroid (17-beta) dehydrogenase 2".

Further reading

  • Labrie Y, Durocher F, Lachance Y; et al. (1995). "The human type II 17 beta-hydroxysteroid dehydrogenase gene encodes two alternatively spliced mRNA species". DNA Cell Biol. 14 (10): 849–61. PMID 7546291.
  • Andersson S, Geissler WM, Patel S, Wu L (1995). "The molecular biology of androgenic 17 beta-hydroxysteroid dehydrogenases". J. Steroid Biochem. Mol. Biol. 53 (1–6): 37–9. PMID 7626483.
  • Durocher F, Morissette J, Labrie Y; et al. (1995). "Mapping of the HSD17B2 gene encoding type II 17 beta-hydroxysteroid dehydrogenase close to D16S422 on chromosome 16q24.1-q24.2". Genomics. 25 (3): 724–6. PMID 7759109.
  • Carsol JL, Martin PM, de Launoit Y (1995). "Characterization of 17 beta-hydroxysteroid dehydrogenase activity and mRNA abundance in human meningioma tumors". Neuroendocrinology. 60 (4): 445–51. PMID 7824086.
  • Wu L, Einstein M, Geissler WM; et al. (1993). "Expression cloning and characterization of human 17 beta-hydroxysteroid dehydrogenase type 2, a microsomal enzyme possessing 20 alpha-hydroxysteroid dehydrogenase activity". J. Biol. Chem. 268 (17): 12964–9. PMID 8099587.
  • Maruyama K, Sugano S (1994). "Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides". Gene. 138 (1–2): 171–4. PMID 8125298.
  • Zhang Y, Word RA, Fesmire S; et al. (1996). "Human ovarian expression of 17 beta-hydroxysteroid dehydrogenase types 1, 2, and 3". J. Clin. Endocrinol. Metab. 81 (10): 3594–8. PMID 8855807.
  • Moghrabi N, Head JR, Andersson S (1997). "Cell type-specific expression of 17 beta-hydroxysteroid dehydrogenase type 2 in human placenta and fetal liver". J. Clin. Endocrinol. Metab. 82 (11): 3872–8. PMID 9360554.
  • Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K; et al. (1997). "Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library". Gene. 200 (1–2): 149–56. PMID 9373149.
  • Corbould AM, Judd SJ, Rodgers RJ (1998). "Expression of types 1, 2, and 3 17 beta-hydroxysteroid dehydrogenase in subcutaneous abdominal and intra-abdominal adipose tissue of women". J. Clin. Endocrinol. Metab. 83 (1): 187–94. PMID 9435439.
  • Dong Y, Qiu QQ, Debear J; et al. (1999). "17Beta-hydroxysteroid dehydrogenases in human bone cells". J. Bone Miner. Res. 13 (10): 1539–46. PMID 9783542.
  • Kitawaki J, Koshiba H, Ishihara H; et al. (2000). "Progesterone induction of 17beta-hydroxysteroid dehydrogenase type 2 during the secretory phase occurs in the endometrium of estrogen-dependent benign diseases but not in normal endometrium". J. Clin. Endocrinol. Metab. 85 (9): 3292–6. PMID 10999824.
  • Sano T, Hirasawa G, Takeyama J; et al. (2001). "17 beta-Hydroxysteroid dehydrogenase type 2 expression and enzyme activity in the human gastrointestinal tract". Clin. Sci. 101 (5): 485–91. PMID 11672453.
  • Lu ML, Huang YW, Lin SX (2002). "Purification, reconstitution, and steady-state kinetics of the trans-membrane 17 beta-hydroxysteroid dehydrogenase 2". J. Biol. Chem. 277 (25): 22123–30. doi:10.1074/jbc.M111726200. PMID 11940569.
  • Provost PR, Blomquist CH, Drolet R; et al. (2002). "Androgen inactivation in human lung fibroblasts: variations in levels of 17 beta-hydroxysteroid dehydrogenase type 2 and 5 alpha-reductase activity compatible with androgen inactivation". J. Clin. Endocrinol. Metab. 87 (8): 3883–92. PMID 12161528.
  • Strausberg RL, Feingold EA, Grouse LH; et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMID 12477932.
  • Oliveira IO, Lhullier C, Brum IS, Spritzer PM (2004). "Gene expression of type 2 17 beta hydroxysteroid dehydrogenase in scalp hairs of hirsute women". Steroids. 68 (7–8): 641–9. PMID 12957669.
  • Oduwole OO, Mäkinen JM, Isomaa VV; et al. (2004). "Sex steroid metabolism in human gastric mucosa: 17 beta-hydroxysteroid dehydrogenase type 2 in normal, inflamed and neoplastic gastric tissues". Anticancer Res. 23 (5A): 3889–97. PMID 14666693.
  • Gerhard DS, Wagner L, Feingold EA; et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMID 15489334.
  • Matsuzaki S, Canis M, Pouly JL; et al. (2006). "Analysis of aromatase and 17beta-hydroxysteroid dehydrogenase type 2 messenger ribonucleic acid expression in deep endometriosis and eutopic endometrium using laser capture microdissection". Fertil. Steril. 85 (2): 308–13. doi:10.1016/j.fertnstert.2005.08.017. PMID 16595205.

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