RRAD

Ras-related associated with diabetes
File:PBB Protein RRAD image.jpg PDB rendering based on 2dpx.
Available structures PDB Ortholog search: Template:Homologene2PDBe PDBe, Template:Homologene2uniprot RCSB List of PDB id codes 2dpx​, 2gjs​
Identifiers
Symbols	RRAD ; RAD1; RAD; REM3
External IDs	Template:OMIM5 Template:MGI HomoloGene: 3071
Gene ontology Molecular function Template:GNF GO Template:GNF GO Template:GNF GO Template:GNF GO Biological process Template:GNF GO
RNA expression pattern
File:PBB GE RRAD 204802 at tn.png
File:PBB GE RRAD 204803 s at tn.png
More reference expression data
Orthologs
Template:GNF Ortholog box
Species	Human	Mouse
Entrez	n/a	n/a
Ensembl	n/a	n/a
UniProt	n/a	n/a
RefSeq (mRNA)	n/a	n/a
RefSeq (protein)	n/a	n/a
Location (UCSC)	n/a	n/a
PubMed search	n/a	n/a

Ras-related associated with diabetes, also known as RRAD, is a human gene.

Further reading

• Doria A, Caldwell JS, Ji L; et al. (1995). "Trinucleotide repeats at the rad locus. Allele distributions in NIDDM and mapping to a 3-cM region on chromosome 16q". Diabetes. 44 (2): 243–7. PMID 7859947.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Zhu J, Reynet C, Caldwell JS, Kahn CR (1995). "Characterization of Rad, a new member of Ras/GTPase superfamily, and its regulation by a unique GTPase-activating protein (GAP)-like activity". J. Biol. Chem. 270 (9): 4805–12. PMID 7876254.CS1 maint: Multiple names: authors list (link)
• Reynet C, Kahn CR (1993). "Rad: a member of the Ras family overexpressed in muscle of type II diabetic humans". Science. 262 (5138): 1441–4. PMID 8248782.
• Zhu J, Bilan PJ, Moyers JS; et al. (1996). "Rad, a novel Ras-related GTPase, interacts with skeletal muscle beta-tropomyosin". J. Biol. Chem. 271 (2): 768–73. PMID 8557685.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Caldwell JS, Moyers JS, Doria A; et al. (1996). "Molecular cloning of the human rad gene: gene structure and complete nucleotide sequence". Biochim. Biophys. Acta. 1316 (3): 145–8. PMID 8781531.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Moyers JS, Bilan PJ, Reynet C, Kahn CR (1996). "Overexpression of Rad inhibits glucose uptake in cultured muscle and fat cells". J. Biol. Chem. 271 (38): 23111–6. PMID 8798502.CS1 maint: Multiple names: authors list (link)
• Moyers JS, Bilan PJ, Zhu J, Kahn CR (1997). "Rad and Rad-related GTPases interact with calmodulin and calmodulin-dependent protein kinase II". J. Biol. Chem. 272 (18): 11832–9. PMID 9115241.CS1 maint: Multiple names: authors list (link)
• Moyers JS, Zhu J, Kahn CR (1998). "Effects of phosphorylation on function of the Rad GTPase". Biochem. J. 333 ( Pt 3): 609–14. PMID 9677319.CS1 maint: Multiple names: authors list (link)
• Finlin BS, Andres DA (1999). "Phosphorylation-dependent association of the Ras-related GTP-binding protein Rem with 14-3-3 proteins". Arch. Biochem. Biophys. 368 (2): 401–12. doi:10.1006/abbi.1999.1316. PMID 10441394.
• Zhu J, Tseng YH, Kantor JD; et al. (2000). "Interaction of the Ras-related protein associated with diabetes rad and the putative tumor metastasis suppressor NM23 provides a novel mechanism of GTPase regulation". Proc. Natl. Acad. Sci. U.S.A. 96 (26): 14911–8. PMID 10611312.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Tseng YH, Vicent D, Zhu J; et al. (2001). "Regulation of growth and tumorigenicity of breast cancer cells by the low molecular weight GTPase Rad and nm23". Cancer Res. 61 (5): 2071–9. PMID 11280768.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Strausberg RL, Feingold EA, Grouse LH; et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMID 12477932.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Gerhard DS, Wagner L, Feingold EA; et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMID 15489334.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Yanuar A, Sakurai S, Kitano K, Hakoshima T (2006). "Expression, purification, crystallization and preliminary crystallographic analysis of human Rad GTPase". Acta Crystallogr. Sect. F Struct. Biol. Cryst. Commun. 61 (Pt 11): 978–80. doi:10.1107/S1744309105031982. PMID 16511212.CS1 maint: Multiple names: authors list (link)
• Yanuar A, Sakurai S, Kitano K, Hakoshima T (2006). "Crystal structure of human Rad GTPase of the RGK-family". Genes Cells. 11 (8): 961–8. doi:10.1111/j.1365-2443.2006.00994.x. PMID 16866878.CS1 maint: Multiple names: authors list (link)
• Suzuki M, Shigematsu H, Shames DS; et al. (2007). "Methylation and gene silencing of the Ras-related GTPase gene in lung and breast cancers". Ann. Surg. Oncol. 14 (4): 1397–404. doi:10.1245/s10434-006-9089-6. PMID 17195088.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Yada H, Murata M, Shimoda K; et al. (2007). "Dominant negative suppression of Rad leads to QT prolongation and causes ventricular arrhythmias via modulation of L-type Ca2+ channels in the heart". Circ. Res. 101 (1): 69–77. doi:10.1161/CIRCRESAHA.106.146399. PMID 17525370.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Szafranski K, Schindler S, Taudien S; et al. "Violating the splicing rules: TG dinucleotides function as alternative 3' splice sites in U2-dependent introns". 8 (8): R154. doi:10.1186/gb-2007-8-8-r154. PMID 17672918.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)